LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 1 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 1. - Dataset (ID:20309)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Neratinib | 1 | 10.06 | 770.25 | 1349 | 1218 | 1.1071 | 1.3324 | MN20160304_L02 | J12 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 12.28 | 770.25 | 1083 | 1358 | 0.7974 | 0.5166 | MN20160304_L02 | E14 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 12.28 | 770.25 | 1405 | 1358 | 1.0345 | 1.0847 | MN20160304_L02 | J12 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 14.50 | 770.25 | 1117 | 1497 | 0.7460 | 0.4735 | MN20160304_L02 | E14 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 14.50 | 770.25 | 1449 | 1497 | 0.9678 | 0.9328 | MN20160304_L02 | J12 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 16.73 | 770.25 | 1164 | 1664 | 0.6993 | 0.4498 | MN20160304_L02 | E14 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 16.73 | 770.25 | 1529 | 1664 | 0.9186 | 0.8529 | MN20160304_L02 | J12 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 18.95 | 770.25 | 1153 | 1832 | 0.6292 | 0.3807 | MN20160304_L02 | E14 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 18.95 | 770.25 | 1548 | 1832 | 0.8448 | 0.7476 | MN20160304_L02 | J12 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 21.17 | 770.25 | 1188 | 2008 | 0.5915 | 0.3681 | MN20160304_L02 | E14 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 21.17 | 770.25 | 1562 | 2008 | 0.7777 | 0.6675 | MN20160304_L02 | J12 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 23.39 | 770.25 | 1138 | 2244 | 0.5070 | 0.2878 | MN20160304_L02 | E14 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 23.39 | 770.25 | 1561 | 2244 | 0.6955 | 0.5806 | MN20160304_L02 | J12 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 25.62 | 770.25 | 1097 | 2514 | 0.4362 | 0.2302 | MN20160304_L02 | E14 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 25.62 | 770.25 | 1549 | 2514 | 0.6159 | 0.5057 | MN20160304_L02 | J12 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 27.84 | 770.25 | 1123 | 2833 | 0.3963 | 0.2222 | MN20160304_L02 | E14 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 27.84 | 770.25 | 1548 | 2833 | 0.5463 | 0.4498 | MN20160304_L02 | J12 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 30.06 | 770.25 | 1097 | 3106 | 0.3532 | 0.1922 | MN20160304_L02 | E14 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 30.06 | 770.25 | 1539 | 3106 | 0.4955 | 0.4107 | MN20160304_L02 | J12 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 32.28 | 770.25 | 1096 | 3392 | 0.3230 | 0.1793 | MN20160304_L02 | E14 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 32.28 | 770.25 | 1558 | 3392 | 0.4592 | 0.3900 | MN20160304_L02 | J12 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 34.50 | 770.25 | 1113 | 3712 | 0.2998 | 0.1762 | MN20160304_L02 | E14 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 34.50 | 770.25 | 1507 | 3712 | 0.4060 | 0.3442 | MN20160304_L02 | J12 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 36.73 | 770.25 | 1119 | 4086 | 0.2739 | 0.1678 | MN20160304_L02 | E14 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 36.73 | 770.25 | 1494 | 4086 | 0.3656 | 0.3168 | MN20160304_L02 | J12 |