Growth rate-corrected (GR) dose-response metric signatures across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 3 of 4: Median, upper quartile, and lower quartile GR metrics per perturbagen. - Dataset (ID:20270)
Small Molecules Studied
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HMS LINCS ID | Name | Alternative Names | LINCS ID | Structure Image | PubChem CID |
---|---|---|---|---|---|
10098-2 | Gefitinib | ZD1839; Iressa | LSM-1098 | 123631 | |
10021-5 | Tozasertib | VX680; MK-0457 | LSM-1021 | 5494449 | |
10513-1 | Nelfinavir | Viracept | 64143 | ||
10511-1 | Mebendazole | Vermox | 4030 | ||
10241-1 | Bortezomib | Velcade | LSM-6281 | 387447 | |
10241 | Bortezomib | Velcade | LSM-6281 | 387447 | |
10241-4 | Bortezomib | Velcade | LSM-6281 | 387447 | |
10239-1 | AG1024 | Tyrphostin AG 1024 | LSM-4262 | 2044 | |
10223-2 | AG1478 | Tyrphostin | LSM-1224 | 2051 | |
10516-1 | Ribavirin | Tribavirin | 37542 | ||
10507-1 | Disulfiram | Tetraethylthiuram disulfide; TETD | 3117 | ||
10208-2 | JNK-IN-5A | TCS JNK 5a; KIN001-188 | LSM-1209 | 766949 | |
10247-1 | Docetaxel | Taxotere | LSM-6360 | 148124 | |
10236-1 | 17-AAG | Tanespimycin | LSM-43239 | 151069 | |
10175-3 | Sunitinib | Sutent; SU11248 | LSM-42800 | 3086686 | |
10282-1 | Vorinostat | suberoylanilide hydroxamic acid (SAHA); Zolinza | LSM-3828 | 5311 | |
10189-2 | Bosutinib | SKI-606 | LSM-1190 | 5328940 | |
10260-1 | Ispinesib | SB-715992 | LSM-5732 | 6851740 | |
10264-1 | Methotrexate | Rheumatrex; Trexall; Amethopterin; MTX | LSM-5690 | 126941 | |
10052-3 | Sirolimus | Rapamycin | LSM-1052 | 5040 | |
10235-2 | Everolimus | RAD001 | LSM-4258 | 53398658 | |
10345-3 | Torkinib | PP242 | LSM-6357 | 57347681 | |
10243-1 | CGC-11047 | PG11047 | LSM-4266 | 476863 | |
10263-1 | LBH589 | Panobinostat | LSM-4284 | 57519507 | |
10102-3 | Taxol | Paclitaxel | LSM-1102 | 441276 |