Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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HCC1395 | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 18.4 | uM | 9254.121 | 0.1347 | -0.6054 | 1.2352 | |
HCC1395 | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 92 | uM | 9254.121 | 0.0888 | -0.7184 | 1.2352 | |
HCC1395 | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 0.000236 | uM | 9258.121 | 0.8420 | 0.3977 | 0.4800 | |
HCC1395 | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 0.00118 | uM | 9258.121 | 1.0096 | 1.0404 | 0.4800 | |
HCC1395 | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 0.00589 | uM | 9258.121 | 1.0065 | 1.0271 | 0.4800 | |
HCC1395 | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 0.0294 | uM | 9258.121 | 0.9609 | 0.8404 | 0.4800 | |
HCC1395 | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 0.147 | uM | 9258.121 | 0.7105 | -0.0188 | 0.4800 | |
HCC1395 | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 0.736 | uM | 9258.121 | 0.5680 | -0.3844 | 0.4800 | |
HCC1395 | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 3.68 | uM | 9258.121 | 0.3369 | -0.7926 | 0.4800 | |
HCC1395 | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 18.4 | uM | 9258.121 | 0.0771 | -0.9904 | 0.4800 | |
HCC1395 | TNBC | Basal B | Doxorubicin | TOP2 | TOP | 92 | uM | 9258.121 | 0.0556 | -0.9952 | 0.4800 | |
HCC1419 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.000221 | uM | 7820.007 | 1.0738 | 1.2194 | 0.6838 | |
HCC1419 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.0011 | uM | 7820.007 | 1.0054 | 1.0159 | 0.6838 | |
HCC1419 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.00552 | uM | 7820.007 | 1.0711 | 1.2114 | 0.6838 | |
HCC1419 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.0276 | uM | 7820.007 | 0.9806 | 0.9434 | 0.6838 | |
HCC1419 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.138 | uM | 7820.007 | 1.1424 | 1.4298 | 0.6838 | |
HCC1419 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.69 | uM | 7820.007 | 0.6290 | 0.0153 | 0.6838 | |
HCC1419 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 3.45 | uM | 7820.007 | 0.3398 | -0.5874 | 0.6838 | |
HCC1419 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 17.2 | uM | 7820.007 | 0.2943 | -0.6656 | 0.6838 | |
HCC1419 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 86.2 | uM | 7820.007 | 0.0403 | -0.9817 | 0.6838 | |
HCC1419 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.000221 | uM | 7821.007 | 0.9631 | 0.8929 | 0.6838 | |
HCC1419 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.0011 | uM | 7821.007 | 0.9013 | 0.7179 | 0.6838 | |
HCC1419 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.00552 | uM | 7821.007 | 0.8778 | 0.6528 | 0.6838 | |
HCC1419 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.0276 | uM | 7821.007 | 0.9026 | 0.7215 | 0.6838 | |
HCC1419 | HER2amp | Luminal | Doxorubicin | TOP2 | TOP | 0.138 | uM | 7821.007 | 0.9918 | 0.9760 | 0.6838 |