Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 10 | uM | 12702.002 | 0.0970 | -0.4252 | 1.8712 | |
| HCC1937 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 10262.002 | 1.0170 | 1.0538 | 0.6356 | |
| HCC1937 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.000128 | uM | 10262.002 | 1.0591 | 1.1889 | 0.6356 | |
| HCC1937 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.00064 | uM | 10262.002 | 0.9805 | 0.9391 | 0.6356 | |
| HCC1937 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.0032 | uM | 10262.002 | 0.9763 | 0.9260 | 0.6356 | |
| HCC1937 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.016 | uM | 10262.002 | 0.6545 | 0.0265 | 0.6356 | |
| HCC1937 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.08 | uM | 10262.002 | 0.6546 | 0.0269 | 0.6356 | |
| HCC1937 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 0.4 | uM | 10262.002 | 0.6316 | -0.0293 | 0.6356 | |
| HCC1937 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 2 | uM | 10262.002 | 0.6793 | 0.0885 | 0.6356 | |
| HCC1937 | TNBC | Basal A | Docetaxel | TUBB | TUBB | 10 | uM | 10262.002 | 0.7124 | 0.1731 | 0.6356 | |
| HCC1954 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 7837.002 | 0.9762 | 0.9725 | 1.7373 | |
| HCC1954 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 0.000128 | uM | 7837.002 | 1.0364 | 1.0415 | 1.7373 | |
| HCC1954 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 0.00064 | uM | 7837.002 | 0.7789 | 0.7321 | 1.7373 | |
| HCC1954 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 0.0032 | uM | 7837.002 | 0.4067 | 0.1917 | 1.7373 | |
| HCC1954 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 0.016 | uM | 7837.002 | 0.0926 | -0.4917 | 1.7373 | |
| HCC1954 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 0.08 | uM | 7837.002 | 0.0332 | -0.7181 | 1.7373 | |
| HCC1954 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 0.4 | uM | 7837.002 | 0.0385 | -0.6933 | 1.7373 | |
| HCC1954 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 2 | uM | 7837.002 | 0.0451 | -0.6641 | 1.7373 | |
| HCC1954 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 10 | uM | 7837.002 | 0.0443 | -0.6673 | 1.7373 | |
| HCC1954 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 0.0000256 | uM | 7839.002 | 0.9741 | 0.9693 | 1.7009 | |
| HCC1954 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 0.000128 | uM | 7839.002 | 1.1430 | 1.1635 | 1.7009 | |
| HCC1954 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 0.00064 | uM | 7839.002 | 0.7710 | 0.7165 | 1.7009 | |
| HCC1954 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 0.0032 | uM | 7839.002 | 0.4886 | 0.3127 | 1.7009 | |
| HCC1954 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 0.016 | uM | 7839.002 | 0.1290 | -0.4000 | 1.7009 | |
| HCC1954 | HER2amp | Basal A | Docetaxel | TUBB | TUBB | 0.08 | uM | 7839.002 | 0.1032 | -0.4739 | 1.7009 |