Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 7912.018 | 0.9976 | 0.9933 | 0.7203 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 9759.006 | 1.0209 | 1.0327 | 1.2714 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 9759.006 | 1.0802 | 1.1251 | 1.2714 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 9759.006 | 0.9764 | 0.9628 | 1.2714 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 9759.006 | 1.0499 | 1.0780 | 1.2714 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 9759.006 | 0.4473 | 0.0623 | 1.2714 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 9759.006 | 1.0411 | 1.0644 | 1.2714 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 9759.006 | 1.0195 | 1.0306 | 1.2714 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 9759.006 | 1.0193 | 1.0304 | 1.2714 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 9759.006 | 0.9744 | 0.9596 | 1.2714 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 9760.026 | 1.0304 | 1.0567 | 1.0724 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 9760.026 | 1.0342 | 1.0637 | 1.0724 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 9760.026 | 1.0628 | 1.1169 | 1.0724 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 9760.026 | 0.9989 | 0.9980 | 1.0724 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 9760.026 | 0.9961 | 0.9928 | 1.0724 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 9760.026 | 1.0185 | 1.0344 | 1.0724 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 9760.026 | 1.0076 | 1.0142 | 1.0724 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 9760.026 | 1.0241 | 1.0449 | 1.0724 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 9760.026 | 0.9711 | 0.9461 | 1.0724 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 10127.123 | 1.1122 | 1.2579 | 0.8767 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 10127.123 | 0.7482 | 0.4367 | 0.8767 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 10127.123 | 1.0006 | 1.0014 | 0.8767 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 10127.123 | 0.9913 | 0.9803 | 0.8767 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 10127.123 | 0.9988 | 0.9972 | 0.8767 | |
| SK-BR-3 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 10127.123 | 0.9608 | 0.9107 | 0.8767 |