Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC202 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 7840.018 | 0.8554 | 0.3680 | 0.4113 | |
| HCC202 | HER2amp | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 7840.018 | 1.0355 | 1.1772 | 0.4113 | |
| HCC2185 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7845.018 | 0.9891 | 0.9520 | 0.4518 | |
| HCC2185 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7845.018 | 1.0539 | 1.2463 | 0.4518 | |
| HCC2185 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7845.018 | 0.9081 | 0.6157 | 0.4518 | |
| HCC2185 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7845.018 | 0.9022 | 0.5925 | 0.4518 | |
| HCC2185 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7845.018 | 1.0019 | 1.0083 | 0.4518 | |
| HCC2185 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7845.018 | 0.9940 | 0.9736 | 0.4518 | |
| HCC2185 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7845.018 | 0.9974 | 0.9883 | 0.4518 | |
| HCC2185 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 7845.018 | 0.8270 | 0.3134 | 0.4518 | |
| HCC2185 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 7845.018 | 0.9518 | 0.7927 | 0.4518 | |
| HCC2185 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7848.042 | 1.1151 | 1.5991 | 0.4157 | |
| HCC2185 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7848.042 | 1.0505 | 1.2514 | 0.4157 | |
| HCC2185 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7848.042 | 1.0432 | 1.2144 | 0.4157 | |
| HCC2185 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7848.042 | 1.0869 | 1.4437 | 0.4157 | |
| HCC2185 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7848.042 | 1.0485 | 1.2414 | 0.4157 | |
| HCC2185 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7848.042 | 1.0336 | 1.1654 | 0.4157 | |
| HCC2185 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7848.042 | 1.0342 | 1.1686 | 0.4157 | |
| HCC2185 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.137 | uM | 7848.042 | 1.0217 | 1.1059 | 0.4157 | |
| HCC2185 | TNBC | Luminal | Cetuximab | EGFR | ErbB | 0.685 | uM | 7848.042 | 0.9759 | 0.8862 | 0.4157 | |
| HCC3153 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7853.042 | 1.0139 | 1.0158 | 1.7624 | |
| HCC3153 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7853.042 | 0.9533 | 0.9464 | 1.7624 | |
| HCC3153 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7853.042 | 0.9942 | 0.9934 | 1.7624 | |
| HCC3153 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7853.042 | 0.9766 | 0.9733 | 1.7624 | |
| HCC3153 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7853.042 | 0.9601 | 0.9543 | 1.7624 |