Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7440.074 | 0.0356 | -0.9981 | 0.4778 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7441.074 | 0.9495 | 0.8796 | 0.8339 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7441.074 | 0.9495 | 0.8796 | 0.8339 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7441.074 | 0.9773 | 0.9457 | 0.8339 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7441.074 | 0.9773 | 0.9457 | 0.8339 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7441.074 | 0.9678 | 0.9230 | 0.8339 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7441.074 | 0.9678 | 0.9230 | 0.8339 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7441.074 | 0.9552 | 0.8930 | 0.8339 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7441.074 | 0.9552 | 0.8930 | 0.8339 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7441.074 | 0.7006 | 0.3053 | 0.8339 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7441.074 | 0.7006 | 0.3053 | 0.8339 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7441.074 | 0.4769 | -0.1771 | 0.8339 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7441.074 | 0.4769 | -0.1771 | 0.8339 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7441.074 | 0.3614 | -0.4099 | 0.8339 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7441.074 | 0.3614 | -0.4099 | 0.8339 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7441.074 | 0.3219 | -0.4864 | 0.8339 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7441.074 | 0.3219 | -0.4864 | 0.8339 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7441.074 | 0.2357 | -0.6465 | 0.8339 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7441.074 | 0.2357 | -0.6465 | 0.8339 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7442.074 | 0.9945 | 0.9866 | 0.8143 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7442.074 | 0.9945 | 0.9866 | 0.8143 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7442.074 | 0.9623 | 0.9077 | 0.8143 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7442.074 | 0.9623 | 0.9077 | 0.8143 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7442.074 | 0.9858 | 0.9652 | 0.8143 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7442.074 | 0.9858 | 0.9652 | 0.8143 |