Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
T47D	HR+	Luminal	Sirolimus	MTOR	MTOR	0.267	uM	9033.068	0.6993	0.3812	0.9662
T47D	HR+	Luminal	Sirolimus	MTOR	MTOR	1.33	uM	9033.068	0.7027	0.3883	0.9662
T47D	HR+	Luminal	Sirolimus	MTOR	MTOR	6.67	uM	9033.068	0.6919	0.3660	0.9662
T47D	HR+	Luminal	Sirolimus	MTOR	MTOR	33.3	uM	9033.068	0.4718	-0.0808	0.9662
T47D	HR+	Luminal	Sirolimus	MTOR	MTOR	167	uM	9033.068	0.1132	-0.7901	0.9662
T47DKBLUC	Unknown	Unknown	Sirolimus	MTOR	MTOR	0.0000853	uM	7546.069	1.0062	1.0142	0.8806
T47DKBLUC	Unknown	Unknown	Sirolimus	MTOR	MTOR	0.000427	uM	7546.069	1.0198	1.0450	0.8806
T47DKBLUC	Unknown	Unknown	Sirolimus	MTOR	MTOR	0.00213	uM	7546.069	0.9554	0.8990	0.8806
T47DKBLUC	Unknown	Unknown	Sirolimus	MTOR	MTOR	0.0107	uM	7546.069	0.9064	0.7887	0.8806
T47DKBLUC	Unknown	Unknown	Sirolimus	MTOR	MTOR	0.0533	uM	7546.069	0.8030	0.5589	0.8806
T47DKBLUC	Unknown	Unknown	Sirolimus	MTOR	MTOR	0.267	uM	7546.069	0.8193	0.5948	0.8806
T47DKBLUC	Unknown	Unknown	Sirolimus	MTOR	MTOR	1.33	uM	7546.069	0.8393	0.6392	0.8806
T47DKBLUC	Unknown	Unknown	Sirolimus	MTOR	MTOR	6.67	uM	7546.069	0.7557	0.4550	0.8806
T47DKBLUC	Unknown	Unknown	Sirolimus	MTOR	MTOR	33.3	uM	7546.069	0.6699	0.2689	0.8806
UACC-812	HER2amp	Luminal	Sirolimus	MTOR	MTOR	0.000427	uM	7926.068	1.0228	1.0484	0.9443
UACC-812	HER2amp	Luminal	Sirolimus	MTOR	MTOR	0.00213	uM	7926.068	0.8731	0.7322	0.9443
UACC-812	HER2amp	Luminal	Sirolimus	MTOR	MTOR	0.0107	uM	7926.068	0.9161	0.8227	0.9443
UACC-812	HER2amp	Luminal	Sirolimus	MTOR	MTOR	0.0533	uM	7926.068	0.7136	0.3991	0.9443
UACC-812	HER2amp	Luminal	Sirolimus	MTOR	MTOR	0.267	uM	7926.068	0.7107	0.3931	0.9443
UACC-812	HER2amp	Luminal	Sirolimus	MTOR	MTOR	1.33	uM	7926.068	0.6470	0.2611	0.9443
UACC-812	HER2amp	Luminal	Sirolimus	MTOR	MTOR	6.67	uM	7926.068	0.7179	0.4080	0.9443
UACC-812	HER2amp	Luminal	Sirolimus	MTOR	MTOR	33.3	uM	7926.068	0.7026	0.3762	0.9443
UACC-812	HER2amp	Luminal	Sirolimus	MTOR	MTOR	167	uM	7926.068	0.6085	0.1819	0.9443
184A1	NM	Basal	Sorafenib	PDGFR/VEGFR/KIT/FLT3	RTK	0.00256	uM	5894.084	0.9542	0.9420	1.5903
184A1	NM	Basal	Sorafenib	PDGFR/VEGFR/KIT/FLT3	RTK	0.0128	uM	5894.084	1.0518	1.0645	1.5903

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)