Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
SUM1315MO2	TNBC	Basal B	Sirolimus	MTOR	MTOR	1.33	uM	7529.068	0.7876	0.3730	0.6347
SUM1315MO2	TNBC	Basal B	Sirolimus	MTOR	MTOR	6.67	uM	7529.068	0.8004	0.4084	0.6347
SUM1315MO2	TNBC	Basal B	Sirolimus	MTOR	MTOR	33.3	uM	7529.068	0.4716	-0.3880	0.6347
SUM1315MO2	TNBC	Basal B	Sirolimus	MTOR	MTOR	167	uM	7529.068	0.0311	-0.9916	0.6347
SUM1315MO2	TNBC	Basal B	Sirolimus	MTOR	MTOR	0.0000853	uM	9044.069	1.0202	1.0418	0.9676
SUM1315MO2	TNBC	Basal B	Sirolimus	MTOR	MTOR	0.000427	uM	9044.069	0.9801	0.9588	0.9676
SUM1315MO2	TNBC	Basal B	Sirolimus	MTOR	MTOR	0.00213	uM	9044.069	0.8662	0.7240	0.9676
SUM1315MO2	TNBC	Basal B	Sirolimus	MTOR	MTOR	0.0107	uM	9044.069	0.8412	0.6728	0.9676
SUM1315MO2	TNBC	Basal B	Sirolimus	MTOR	MTOR	0.0533	uM	9044.069	0.7784	0.5437	0.9676
SUM1315MO2	TNBC	Basal B	Sirolimus	MTOR	MTOR	0.267	uM	9044.069	0.7745	0.5357	0.9676
SUM1315MO2	TNBC	Basal B	Sirolimus	MTOR	MTOR	1.33	uM	9044.069	0.8117	0.6121	0.9676
SUM1315MO2	TNBC	Basal B	Sirolimus	MTOR	MTOR	6.67	uM	9044.069	0.6873	0.3573	0.9676
SUM1315MO2	TNBC	Basal B	Sirolimus	MTOR	MTOR	33.3	uM	9044.069	0.3277	-0.3686	0.9676
SUM149PT	TNBC	Basal B	Sirolimus	MTOR	MTOR	0.000427	uM	7917.068	1.0185	1.0126	2.9241
SUM149PT	TNBC	Basal B	Sirolimus	MTOR	MTOR	0.00213	uM	7917.068	0.9523	0.9668	2.9241
SUM149PT	TNBC	Basal B	Sirolimus	MTOR	MTOR	0.0107	uM	7917.068	0.8742	0.9101	2.9241
SUM149PT	TNBC	Basal B	Sirolimus	MTOR	MTOR	0.0533	uM	7917.068	0.8003	0.8533	2.9241
SUM149PT	TNBC	Basal B	Sirolimus	MTOR	MTOR	0.267	uM	7917.068	0.7988	0.8521	2.9241
SUM149PT	TNBC	Basal B	Sirolimus	MTOR	MTOR	1.33	uM	7917.068	0.7440	0.8076	2.9241
SUM149PT	TNBC	Basal B	Sirolimus	MTOR	MTOR	6.67	uM	7917.068	0.7105	0.7794	2.9241
SUM149PT	TNBC	Basal B	Sirolimus	MTOR	MTOR	33.3	uM	7917.068	0.0105	-0.5788	2.9241
SUM149PT	TNBC	Basal B	Sirolimus	MTOR	MTOR	167	uM	7917.068	0.0079	-0.6188	2.9241
SUM159PT	TNBC	Basal B	Sirolimus	MTOR	MTOR	0.000427	uM	7920.068	0.9663	0.9843	4.3418
SUM159PT	TNBC	Basal B	Sirolimus	MTOR	MTOR	0.00213	uM	7920.068	0.8521	0.9276	4.3418
SUM159PT	TNBC	Basal B	Sirolimus	MTOR	MTOR	0.0107	uM	7920.068	0.7084	0.8473	4.3418

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)