Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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SUM1315MO2 | TNBC | Basal B | PD 98059 | MEK | MAPK | 0.016 | uM | 10875.152 | 0.9320 | 0.8200 | 0.7465 | |
SUM1315MO2 | TNBC | Basal B | PD 98059 | MEK | MAPK | 0.08 | uM | 10875.152 | 0.9387 | 0.8374 | 0.7465 | |
SUM1315MO2 | TNBC | Basal B | PD 98059 | MEK | MAPK | 0.4 | uM | 10875.152 | 0.9357 | 0.8296 | 0.7465 | |
SUM1315MO2 | TNBC | Basal B | PD 98059 | MEK | MAPK | 2 | uM | 10875.152 | 0.9285 | 0.8108 | 0.7465 | |
SUM1315MO2 | TNBC | Basal B | PD 98059 | MEK | MAPK | 10 | uM | 10875.152 | 0.8728 | 0.6669 | 0.7465 | |
SUM1315MO2 | TNBC | Basal B | PD 98059 | MEK | MAPK | 50 | uM | 10875.152 | 0.8983 | 0.7323 | 0.7465 | |
SUM1315MO2 | TNBC | Basal B | PD 98059 | MEK | MAPK | 0.000128 | uM | 12428.152 | 0.9480 | 0.8811 | 0.8719 | |
SUM1315MO2 | TNBC | Basal B | PD 98059 | MEK | MAPK | 0.00064 | uM | 12428.152 | 0.9996 | 0.9990 | 0.8719 | |
SUM1315MO2 | TNBC | Basal B | PD 98059 | MEK | MAPK | 0.0032 | uM | 12428.152 | 0.9577 | 0.9032 | 0.8719 | |
SUM1315MO2 | TNBC | Basal B | PD 98059 | MEK | MAPK | 0.016 | uM | 12428.152 | 0.9563 | 0.9000 | 0.8719 | |
SUM1315MO2 | TNBC | Basal B | PD 98059 | MEK | MAPK | 0.08 | uM | 12428.152 | 0.9658 | 0.9218 | 0.8719 | |
SUM1315MO2 | TNBC | Basal B | PD 98059 | MEK | MAPK | 0.4 | uM | 12428.152 | 1.0128 | 1.0295 | 0.8719 | |
SUM1315MO2 | TNBC | Basal B | PD 98059 | MEK | MAPK | 2 | uM | 12428.152 | 1.0088 | 1.0203 | 0.8719 | |
SUM1315MO2 | TNBC | Basal B | PD 98059 | MEK | MAPK | 10 | uM | 12428.152 | 0.9723 | 0.9365 | 0.8719 | |
SUM1315MO2 | TNBC | Basal B | PD 98059 | MEK | MAPK | 50 | uM | 12428.152 | 0.8529 | 0.6663 | 0.8719 | |
SUM149PT | TNBC | Basal B | PD 98059 | MEK | MAPK | 0.000128 | uM | 10819.152 | 0.9490 | 0.9486 | 2.0116 | |
SUM149PT | TNBC | Basal B | PD 98059 | MEK | MAPK | 0.00064 | uM | 10819.152 | 0.9620 | 0.9619 | 2.0116 | |
SUM149PT | TNBC | Basal B | PD 98059 | MEK | MAPK | 0.0032 | uM | 10819.152 | 0.9984 | 0.9984 | 2.0116 | |
SUM149PT | TNBC | Basal B | PD 98059 | MEK | MAPK | 0.016 | uM | 10819.152 | 0.9981 | 0.9981 | 2.0116 | |
SUM149PT | TNBC | Basal B | PD 98059 | MEK | MAPK | 0.08 | uM | 10819.152 | 1.0122 | 1.0121 | 2.0116 | |
SUM149PT | TNBC | Basal B | PD 98059 | MEK | MAPK | 0.4 | uM | 10819.152 | 0.9675 | 0.9674 | 2.0116 | |
SUM149PT | TNBC | Basal B | PD 98059 | MEK | MAPK | 2 | uM | 10819.152 | 0.9482 | 0.9478 | 2.0116 | |
SUM149PT | TNBC | Basal B | PD 98059 | MEK | MAPK | 10 | uM | 10819.152 | 0.8869 | 0.8842 | 2.0116 | |
SUM149PT | TNBC | Basal B | PD 98059 | MEK | MAPK | 50 | uM | 10819.152 | 0.7778 | 0.7651 | 2.0116 | |
SUM149PT | TNBC | Basal B | PD 98059 | MEK | MAPK | 0.000256 | uM | 11937.159 | 0.9681 | 0.9710 | 2.2200 |