Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
SUM1315MO2
TNBC
Basal B
PD 98059
MEK
MAPK
0.016
uM
10875.152
0.9320 0.8200 0.7465
SUM1315MO2
TNBC
Basal B
PD 98059
MEK
MAPK
0.08
uM
10875.152
0.9387 0.8374 0.7465
SUM1315MO2
TNBC
Basal B
PD 98059
MEK
MAPK
0.4
uM
10875.152
0.9357 0.8296 0.7465
SUM1315MO2
TNBC
Basal B
PD 98059
MEK
MAPK
2
uM
10875.152
0.9285 0.8108 0.7465
SUM1315MO2
TNBC
Basal B
PD 98059
MEK
MAPK
10
uM
10875.152
0.8728 0.6669 0.7465
SUM1315MO2
TNBC
Basal B
PD 98059
MEK
MAPK
50
uM
10875.152
0.8983 0.7323 0.7465
SUM1315MO2
TNBC
Basal B
PD 98059
MEK
MAPK
0.000128
uM
12428.152
0.9480 0.8811 0.8719
SUM1315MO2
TNBC
Basal B
PD 98059
MEK
MAPK
0.00064
uM
12428.152
0.9996 0.9990 0.8719
SUM1315MO2
TNBC
Basal B
PD 98059
MEK
MAPK
0.0032
uM
12428.152
0.9577 0.9032 0.8719
SUM1315MO2
TNBC
Basal B
PD 98059
MEK
MAPK
0.016
uM
12428.152
0.9563 0.9000 0.8719
SUM1315MO2
TNBC
Basal B
PD 98059
MEK
MAPK
0.08
uM
12428.152
0.9658 0.9218 0.8719
SUM1315MO2
TNBC
Basal B
PD 98059
MEK
MAPK
0.4
uM
12428.152
1.0128 1.0295 0.8719
SUM1315MO2
TNBC
Basal B
PD 98059
MEK
MAPK
2
uM
12428.152
1.0088 1.0203 0.8719
SUM1315MO2
TNBC
Basal B
PD 98059
MEK
MAPK
10
uM
12428.152
0.9723 0.9365 0.8719
SUM1315MO2
TNBC
Basal B
PD 98059
MEK
MAPK
50
uM
12428.152
0.8529 0.6663 0.8719
SUM149PT
TNBC
Basal B
PD 98059
MEK
MAPK
0.000128
uM
10819.152
0.9490 0.9486 2.0116
SUM149PT
TNBC
Basal B
PD 98059
MEK
MAPK
0.00064
uM
10819.152
0.9620 0.9619 2.0116
SUM149PT
TNBC
Basal B
PD 98059
MEK
MAPK
0.0032
uM
10819.152
0.9984 0.9984 2.0116
SUM149PT
TNBC
Basal B
PD 98059
MEK
MAPK
0.016
uM
10819.152
0.9981 0.9981 2.0116
SUM149PT
TNBC
Basal B
PD 98059
MEK
MAPK
0.08
uM
10819.152
1.0122 1.0121 2.0116
SUM149PT
TNBC
Basal B
PD 98059
MEK
MAPK
0.4
uM
10819.152
0.9675 0.9674 2.0116
SUM149PT
TNBC
Basal B
PD 98059
MEK
MAPK
2
uM
10819.152
0.9482 0.9478 2.0116
SUM149PT
TNBC
Basal B
PD 98059
MEK
MAPK
10
uM
10819.152
0.8869 0.8842 2.0116
SUM149PT
TNBC
Basal B
PD 98059
MEK
MAPK
50
uM
10819.152
0.7778 0.7651 2.0116
SUM149PT
TNBC
Basal B
PD 98059
MEK
MAPK
0.000256
uM
11937.159
0.9681 0.9710 2.2200