Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14628.189 | 0.3011 | -0.5916 | 0.7555 | |
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14628.189 | 0.0181 | -0.9901 | 0.7555 | |
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14628.189 | 0.0181 | -0.9901 | 0.7555 | |
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14628.189 | 0.0347 | -0.9767 | 0.7555 | |
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14628.189 | 0.0347 | -0.9767 | 0.7555 | |
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14628.189 | 0.0369 | -0.9747 | 0.7555 | |
| T47DKBLUC | Unknown | Unknown | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14628.189 | 0.0369 | -0.9747 | 0.7555 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10580.145 | 0.9097 | 0.8003 | 0.9000 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10580.145 | 0.9097 | 0.8003 | 0.9000 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10580.145 | 0.9112 | 0.8038 | 0.9000 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10580.145 | 0.9112 | 0.8038 | 0.9000 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10580.145 | 0.9214 | 0.8260 | 0.9000 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10580.145 | 0.9214 | 0.8260 | 0.9000 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10580.145 | 0.8983 | 0.7752 | 0.9000 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10580.145 | 0.8983 | 0.7752 | 0.9000 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10580.145 | 0.8676 | 0.7079 | 0.9000 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10580.145 | 0.8676 | 0.7079 | 0.9000 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10580.145 | 0.3992 | -0.2791 | 0.9000 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10580.145 | 0.3992 | -0.2791 | 0.9000 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10580.145 | 0.2958 | -0.4833 | 0.9000 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10580.145 | 0.2958 | -0.4833 | 0.9000 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10580.145 | 0.1804 | -0.7017 | 0.9000 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10580.145 | 0.1804 | -0.7017 | 0.9000 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10580.145 | 0.2258 | -0.6172 | 0.9000 | |
| UACC-812 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10580.145 | 0.2258 | -0.6172 | 0.9000 |