Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.667 | uM | 7507.098 | 0.8997 | 0.8024 | 1.0164 | |
| MDA-MB-361 | HER2amp | Luminal | Lapatinib | EGFR/HER2 | ErbB | 3.33 | uM | 7507.098 | 0.7406 | 0.4884 | 1.0164 | |
| MDA-MB-361 | HER2amp | Luminal | Lapatinib | EGFR/HER2 | ErbB | 16.7 | uM | 7507.098 | 0.7844 | 0.5749 | 1.0164 | |
| MDA-MB-361 | HER2amp | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.0000427 | uM | 7508.098 | 1.0247 | 1.0622 | 0.7973 | |
| MDA-MB-361 | HER2amp | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.000213 | uM | 7508.098 | 0.9748 | 0.9370 | 0.7973 | |
| MDA-MB-361 | HER2amp | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.00107 | uM | 7508.098 | 1.0191 | 1.0480 | 0.7973 | |
| MDA-MB-361 | HER2amp | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.00533 | uM | 7508.098 | 1.0335 | 1.0844 | 0.7973 | |
| MDA-MB-361 | HER2amp | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.0267 | uM | 7508.098 | 0.9944 | 0.9859 | 0.7973 | |
| MDA-MB-361 | HER2amp | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.133 | uM | 7508.098 | 1.0290 | 1.0729 | 0.7973 | |
| MDA-MB-361 | HER2amp | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.667 | uM | 7508.098 | 0.8725 | 0.6854 | 0.7973 | |
| MDA-MB-361 | HER2amp | Luminal | Lapatinib | EGFR/HER2 | ErbB | 3.33 | uM | 7508.098 | 0.6702 | 0.2108 | 0.7973 | |
| MDA-MB-361 | HER2amp | Luminal | Lapatinib | EGFR/HER2 | ErbB | 16.7 | uM | 7508.098 | 0.6240 | 0.1071 | 0.7973 | |
| MDA-MB-415 | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.0000427 | uM | 7510.098 | 0.9482 | 0.8914 | 0.9528 | |
| MDA-MB-415 | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.000213 | uM | 7510.098 | 0.9963 | 0.9922 | 0.9528 | |
| MDA-MB-415 | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.00107 | uM | 7510.098 | 0.9526 | 0.9005 | 0.9528 | |
| MDA-MB-415 | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.00533 | uM | 7510.098 | 1.0476 | 1.1001 | 0.9528 | |
| MDA-MB-415 | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.0267 | uM | 7510.098 | 1.0037 | 1.0078 | 0.9528 | |
| MDA-MB-415 | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.133 | uM | 7510.098 | 0.9553 | 0.9062 | 0.9528 | |
| MDA-MB-415 | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.667 | uM | 7510.098 | 0.9541 | 0.9037 | 0.9528 | |
| MDA-MB-415 | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 3.33 | uM | 7510.098 | 1.1341 | 1.2824 | 0.9528 | |
| MDA-MB-415 | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 16.7 | uM | 7510.098 | 0.9818 | 0.9619 | 0.9528 | |
| MDA-MB-415 | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.0000427 | uM | 7511.098 | 1.0035 | 1.0058 | 1.2032 | |
| MDA-MB-415 | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.000213 | uM | 7511.098 | 0.9692 | 0.9486 | 1.2032 | |
| MDA-MB-415 | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.00107 | uM | 7511.098 | 1.0067 | 1.0111 | 1.2032 | |
| MDA-MB-415 | HR+ | Luminal | Lapatinib | EGFR/HER2 | ErbB | 0.00533 | uM | 7511.098 | 0.9877 | 0.9794 | 1.2032 |