Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM229PE | TNBC | - | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7537.095 | 0.6536 | 0.6146 | 1.9867 | |
| SUM229PE | TNBC | - | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7537.095 | 0.3457 | 0.1717 | 1.9867 | |
| SUM229PE | TNBC | - | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7537.095 | 0.3261 | 0.1377 | 1.9867 | |
| SUM229PE | TNBC | - | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7537.095 | 0.2526 | 0.0006 | 1.9867 | |
| SUM229PE | TNBC | - | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7537.095 | 0.2595 | 0.0143 | 1.9867 | |
| SUM229PE | TNBC | - | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7537.095 | 0.2903 | 0.0732 | 1.9867 | |
| SUM229PE | TNBC | - | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7537.095 | 0.1237 | -0.3015 | 1.9867 | |
| SUM229PE | TNBC | - | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7537.095 | 0.0064 | -0.8426 | 1.9867 | |
| SUM52PE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7539.095 | 0.9606 | 0.9307 | 1.1392 | |
| SUM52PE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7539.095 | 0.8415 | 0.7190 | 1.1392 | |
| SUM52PE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7539.095 | 0.9500 | 0.9119 | 1.1392 | |
| SUM52PE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7539.095 | 0.6410 | 0.3537 | 1.1392 | |
| SUM52PE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7539.095 | 0.3511 | -0.2021 | 1.1392 | |
| SUM52PE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7539.095 | 0.3188 | -0.2667 | 1.1392 | |
| SUM52PE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7539.095 | 0.4639 | 0.0192 | 1.1392 | |
| SUM52PE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7539.095 | 0.2538 | -0.3998 | 1.1392 | |
| SUM52PE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7539.095 | 0.0015 | -0.9933 | 1.1392 | |
| SUM52PE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7541.095 | 0.8905 | 0.8466 | 1.4542 | |
| SUM52PE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7541.095 | 0.5234 | 0.2815 | 1.4542 | |
| SUM52PE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7541.095 | 0.3459 | -0.0362 | 1.4542 | |
| SUM52PE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7541.095 | 0.3103 | -0.1056 | 1.4542 | |
| SUM52PE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7541.095 | 0.2680 | -0.1912 | 1.4542 | |
| SUM52PE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7541.095 | 0.2573 | -0.2136 | 1.4542 | |
| SUM52PE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7541.095 | 0.3731 | 0.0154 | 1.4542 | |
| SUM52PE | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7541.095 | 0.2831 | -0.1603 | 1.4542 |