Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-175-VII | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.00253 | uM | 7499.094 | 0.7726 | 0.3370 | 0.6407 | |
| MDA-MB-175-VII | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7499.094 | 0.7969 | 0.4033 | 0.6407 | |
| MDA-MB-175-VII | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0632 | uM | 7499.094 | 0.7495 | 0.2752 | 0.6407 | |
| MDA-MB-175-VII | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7499.094 | 0.7288 | 0.2206 | 0.6407 | |
| MDA-MB-175-VII | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7499.094 | 0.6573 | 0.0388 | 0.6407 | |
| MDA-MB-175-VII | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7499.094 | 0.4030 | -0.5158 | 0.6407 | |
| MDA-MB-175-VII | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 39.5 | uM | 7499.094 | 0.0014 | -0.9999 | 0.6407 | |
| MDA-MB-175-VII | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 197 | uM | 7499.094 | 0.2305 | -0.7976 | 0.6407 | |
| MDA-MB-175-VII | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7500.095 | 1.0701 | 1.3160 | 0.4619 | |
| MDA-MB-175-VII | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7500.095 | 0.9335 | 0.7233 | 0.4619 | |
| MDA-MB-175-VII | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7500.095 | 0.7460 | 0.0605 | 0.4619 | |
| MDA-MB-175-VII | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7500.095 | 0.8760 | 0.5015 | 0.4619 | |
| MDA-MB-175-VII | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7500.095 | 0.8684 | 0.4736 | 0.4619 | |
| MDA-MB-175-VII | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7500.095 | 0.6940 | -0.0931 | 0.4619 | |
| MDA-MB-175-VII | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7500.095 | 0.9181 | 0.6623 | 0.4619 | |
| MDA-MB-175-VII | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7500.095 | 0.5166 | -0.5213 | 0.4619 | |
| MDA-MB-175-VII | HR+ | Luminal | Ixabepilone | TUBB | TUBB | 39.4 | uM | 7500.095 | 0.0345 | -0.9986 | 0.4619 | |
| MDA-MB-231 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000101 | uM | 7504.095 | 0.9408 | 0.9421 | 2.0796 | |
| MDA-MB-231 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.000505 | uM | 7504.095 | 0.6662 | 0.6451 | 2.0796 | |
| MDA-MB-231 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.00252 | uM | 7504.095 | 0.3033 | 0.1269 | 2.0796 | |
| MDA-MB-231 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0126 | uM | 7504.095 | 0.2603 | 0.0470 | 2.0796 | |
| MDA-MB-231 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.0631 | uM | 7504.095 | 0.1880 | -0.1047 | 2.0796 | |
| MDA-MB-231 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 0.316 | uM | 7504.095 | 0.2025 | -0.0720 | 2.0796 | |
| MDA-MB-231 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 1.58 | uM | 7504.095 | 0.2070 | -0.0622 | 2.0796 | |
| MDA-MB-231 | TNBC | Basal B | Ixabepilone | TUBB | TUBB | 7.89 | uM | 7504.095 | 0.2411 | 0.0092 | 2.0796 |