Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 30.7 | uM | 7906.017 | 1.2934 | 2.9209 | 0.3822 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 154 | uM | 7906.017 | 1.0585 | 1.3208 | 0.3822 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 769 | uM | 7906.017 | 0.5614 | -0.5586 | 0.3822 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 3840 | uM | 7906.017 | 0.2931 | -0.9194 | 0.3822 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 19200 | uM | 7906.017 | 0.2004 | -0.9702 | 0.3822 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.0492 | uM | 7907.017 | 0.9055 | 0.8646 | 1.4157 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.246 | uM | 7907.017 | 1.1445 | 1.2000 | 1.4157 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 1.23 | uM | 7907.017 | 0.8925 | 0.8457 | 1.4157 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 6.15 | uM | 7907.017 | 0.9961 | 0.9944 | 1.4157 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 30.7 | uM | 7907.017 | 0.9095 | 0.8704 | 1.4157 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 154 | uM | 7907.017 | 0.6020 | 0.3974 | 1.4157 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 769 | uM | 7907.017 | 0.3356 | -0.0752 | 1.4157 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 3840 | uM | 7907.017 | 0.2039 | -0.3495 | 1.4157 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 19200 | uM | 7907.017 | 0.1065 | -0.5890 | 1.4157 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.0492 | uM | 7909.13 | 0.9126 | 0.8837 | 1.5270 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 0.246 | uM | 7909.13 | 1.1666 | 1.2124 | 1.5270 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 1.23 | uM | 7909.13 | 0.8439 | 0.7896 | 1.5270 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 6.15 | uM | 7909.13 | 1.0784 | 1.1013 | 1.5270 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 30.7 | uM | 7909.13 | 1.0587 | 1.0761 | 1.5270 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 154 | uM | 7909.13 | 0.7918 | 0.7164 | 1.5270 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 769 | uM | 7909.13 | 0.3978 | 0.0935 | 1.5270 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 3840 | uM | 7909.13 | 0.2760 | -0.1393 | 1.5270 | |
| MDA-MB-468 | TNBC | Basal A | 5-FU | TYMS | TYMS | 19200 | uM | 7909.13 | 0.1883 | -0.3300 | 1.5270 | |
| SK-BR-3 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 0.0492 | uM | 9760.131 | 1.0375 | 1.0760 | 0.9878 | |
| SK-BR-3 | HER2amp | Luminal | 5-FU | TYMS | TYMS | 0.246 | uM | 9760.131 | 0.8432 | 0.6829 | 0.9878 |