Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | IKK16 | IKK | NFKB | 0.533 | uM | 7539.093 | 0.7424 | 0.6587 | 1.5919 | |
| SUM52PE | HR+ | Luminal | IKK16 | IKK | NFKB | 2.67 | uM | 7539.093 | 0.4573 | 0.2235 | 1.5919 | |
| SUM52PE | HR+ | Luminal | IKK16 | IKK | NFKB | 13.3 | uM | 7539.093 | 0.0150 | -0.8568 | 1.5919 | |
| SUM52PE | HR+ | Luminal | IKK16 | IKK | NFKB | 66.7 | uM | 7539.093 | 0.0061 | -0.9190 | 1.5919 | |
| T47D | HR+ | Luminal | IKK16 | IKK | NFKB | 0.000171 | uM | 7542.1 | 0.9728 | 0.9586 | 1.3201 | |
| T47D | HR+ | Luminal | IKK16 | IKK | NFKB | 0.000853 | uM | 7542.1 | 0.9833 | 0.9746 | 1.3201 | |
| T47D | HR+ | Luminal | IKK16 | IKK | NFKB | 0.00427 | uM | 7542.1 | 0.9885 | 0.9825 | 1.3201 | |
| T47D | HR+ | Luminal | IKK16 | IKK | NFKB | 0.0213 | uM | 7542.1 | 0.9801 | 0.9697 | 1.3201 | |
| T47D | HR+ | Luminal | IKK16 | IKK | NFKB | 0.107 | uM | 7542.1 | 0.9642 | 0.9456 | 1.3201 | |
| T47D | HR+ | Luminal | IKK16 | IKK | NFKB | 0.533 | uM | 7542.1 | 0.9893 | 0.9837 | 1.3201 | |
| T47D | HR+ | Luminal | IKK16 | IKK | NFKB | 2.67 | uM | 7542.1 | 0.7696 | 0.6401 | 1.3201 | |
| T47D | HR+ | Luminal | IKK16 | IKK | NFKB | 13.3 | uM | 7542.1 | 0.0111 | -0.9340 | 1.3201 | |
| T47D | HR+ | Luminal | IKK16 | IKK | NFKB | 66.7 | uM | 7542.1 | 0.0088 | -0.9445 | 1.3201 | |
| T47DKBLUC | Unknown | Unknown | IKK16 | IKK | NFKB | 0.000171 | uM | 7544.093 | 1.0220 | 1.0355 | 1.2382 | |
| T47DKBLUC | Unknown | Unknown | IKK16 | IKK | NFKB | 0.000853 | uM | 7544.093 | 0.9062 | 0.8471 | 1.2382 | |
| T47DKBLUC | Unknown | Unknown | IKK16 | IKK | NFKB | 0.00427 | uM | 7544.093 | 0.9459 | 0.9121 | 1.2382 | |
| T47DKBLUC | Unknown | Unknown | IKK16 | IKK | NFKB | 0.0213 | uM | 7544.093 | 0.9388 | 0.9006 | 1.2382 | |
| T47DKBLUC | Unknown | Unknown | IKK16 | IKK | NFKB | 0.107 | uM | 7544.093 | 0.9581 | 0.9321 | 1.2382 | |
| T47DKBLUC | Unknown | Unknown | IKK16 | IKK | NFKB | 0.533 | uM | 7544.093 | 0.9104 | 0.8540 | 1.2382 | |
| T47DKBLUC | Unknown | Unknown | IKK16 | IKK | NFKB | 2.67 | uM | 7544.093 | 0.9308 | 0.8875 | 1.2382 | |
| T47DKBLUC | Unknown | Unknown | IKK16 | IKK | NFKB | 13.3 | uM | 7544.093 | 0.0259 | -0.8955 | 1.2382 | |
| T47DKBLUC | Unknown | Unknown | IKK16 | IKK | NFKB | 66.7 | uM | 7544.093 | 0.0099 | -0.9518 | 1.2382 | |
| T47DKBLUC | Unknown | Unknown | IKK16 | IKK | NFKB | 0.000171 | uM | 7545.1 | 0.9346 | 0.8847 | 1.1396 | |
| T47DKBLUC | Unknown | Unknown | IKK16 | IKK | NFKB | 0.000853 | uM | 7545.1 | 0.9313 | 0.8788 | 1.1396 | |
| T47DKBLUC | Unknown | Unknown | IKK16 | IKK | NFKB | 0.00427 | uM | 7545.1 | 0.9814 | 0.9672 | 1.1396 |