Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
HCC38	TNBC	Basal B	GM6001	MMP	MMP	0.0107	uM	7468.096	0.9546	0.9417	1.5683
HCC38	TNBC	Basal B	GM6001	MMP	MMP	0.0533	uM	7468.096	1.0005	1.0006	1.5683
HCC38	TNBC	Basal B	GM6001	MMP	MMP	0.267	uM	7468.096	0.9474	0.9323	1.5683
HCC38	TNBC	Basal B	GM6001	MMP	MMP	1.33	uM	7468.096	0.8833	0.8479	1.5683
HCC38	TNBC	Basal B	GM6001	MMP	MMP	6.67	uM	7468.096	0.8987	0.8683	1.5683
HCC38	TNBC	Basal B	GM6001	MMP	MMP	33.3	uM	7468.096	0.9675	0.9583	1.5683
HCC70	TNBC	Basal A	GM6001	MMP	MMP	0.0000853	uM	7470.096	0.9705	0.9383	0.9576
HCC70	TNBC	Basal A	GM6001	MMP	MMP	0.000427	uM	7470.096	0.9837	0.9661	0.9576
HCC70	TNBC	Basal A	GM6001	MMP	MMP	0.00213	uM	7470.096	1.0081	1.0170	0.9576
HCC70	TNBC	Basal A	GM6001	MMP	MMP	0.0107	uM	7470.096	1.0096	1.0202	0.9576
HCC70	TNBC	Basal A	GM6001	MMP	MMP	0.0533	uM	7470.096	1.0133	1.0279	0.9576
HCC70	TNBC	Basal A	GM6001	MMP	MMP	0.267	uM	7470.096	0.9046	0.8012	0.9576
HCC70	TNBC	Basal A	GM6001	MMP	MMP	1.33	uM	7470.096	0.8400	0.6670	0.9576
HCC70	TNBC	Basal A	GM6001	MMP	MMP	6.67	uM	7470.096	0.7523	0.4858	0.9576
HCC70	TNBC	Basal A	GM6001	MMP	MMP	33.3	uM	7470.096	0.6336	0.2418	0.9576
MCF 10A	NM	Basal B	GM6001	MMP	MMP	0.0000853	uM	7485.096	0.9260	0.9580	3.6265
MCF 10A	NM	Basal B	GM6001	MMP	MMP	0.000427	uM	7485.096	0.9727	0.9848	3.6265
MCF 10A	NM	Basal B	GM6001	MMP	MMP	0.00213	uM	7485.096	0.9574	0.9762	3.6265
MCF 10A	NM	Basal B	GM6001	MMP	MMP	0.0107	uM	7485.096	1.0093	1.0051	3.6265
MCF 10A	NM	Basal B	GM6001	MMP	MMP	0.0533	uM	7485.096	0.8902	0.9369	3.6265
MCF 10A	NM	Basal B	GM6001	MMP	MMP	0.267	uM	7485.096	0.9569	0.9759	3.6265
MCF 10A	NM	Basal B	GM6001	MMP	MMP	1.33	uM	7485.096	0.8887	0.9360	3.6265
MCF 10A	NM	Basal B	GM6001	MMP	MMP	6.67	uM	7485.096	0.9034	0.9447	3.6265
MCF 10A	NM	Basal B	GM6001	MMP	MMP	33.3	uM	7485.096	0.8755	0.9280	3.6265
MCF12A	NM	Basal B	GM6001	MMP	MMP	0.0000853	uM	7490.096	0.9514	0.9617	2.5767
MCF12A	NM	Basal B	GM6001	MMP	MMP	0.000427	uM	7490.096	0.9833	0.9869	2.5767
MCF12A	NM	Basal B	GM6001	MMP	MMP	0.00213	uM	7490.096	0.9702	0.9767	2.5767
MCF12A	NM	Basal B	GM6001	MMP	MMP	0.0107	uM	7490.096	0.9776	0.9825	2.5767
MCF12A	NM	Basal B	GM6001	MMP	MMP	0.0533	uM	7490.096	1.0021	1.0016	2.5767
MCF12A	NM	Basal B	GM6001	MMP	MMP	0.267	uM	7490.096	0.9721	0.9781	2.5767
MCF12A	NM	Basal B	GM6001	MMP	MMP	1.33	uM	7490.096	0.9746	0.9802	2.5767
MCF12A	NM	Basal B	GM6001	MMP	MMP	6.67	uM	7490.096	0.9404	0.9529	2.5767
MCF12A	NM	Basal B	GM6001	MMP	MMP	33.3	uM	7490.096	0.9311	0.9454	2.5767
MCF7	HR+	Luminal	GM6001	MMP	MMP	0.0000853	uM	7493.096	0.9723	0.9524	1.1669
MCF7	HR+	Luminal	GM6001	MMP	MMP	0.000427	uM	7493.096	0.9742	0.9556	1.1669
MCF7	HR+	Luminal	GM6001	MMP	MMP	0.00213	uM	7493.096	0.9368	0.8911	1.1669
MCF7	HR+	Luminal	GM6001	MMP	MMP	0.0107	uM	7493.096	0.9910	0.9845	1.1669
MCF7	HR+	Luminal	GM6001	MMP	MMP	0.0533	uM	7493.096	1.0024	1.0041	1.1669
MCF7	HR+	Luminal	GM6001	MMP	MMP	0.267	uM	7493.096	0.9545	0.9217	1.1669
MCF7	HR+	Luminal	GM6001	MMP	MMP	1.33	uM	7493.096	0.9372	0.8918	1.1669
MCF7	HR+	Luminal	GM6001	MMP	MMP	6.67	uM	7493.096	0.9420	0.9002	1.1669
MCF7	HR+	Luminal	GM6001	MMP	MMP	33.3	uM	7493.096	0.9105	0.8456	1.1669
MDA-MB-157	TNBC	Basal B	GM6001	MMP	MMP	0.0000853	uM	7496.096	0.9356	0.8801	1.0771
MDA-MB-157	TNBC	Basal B	GM6001	MMP	MMP	0.000427	uM	7496.096	0.9208	0.8526	1.0771
MDA-MB-157	TNBC	Basal B	GM6001	MMP	MMP	0.00213	uM	7496.096	0.9116	0.8352	1.0771
MDA-MB-157	TNBC	Basal B	GM6001	MMP	MMP	0.0107	uM	7496.096	0.9911	0.9834	1.0771
MDA-MB-157	TNBC	Basal B	GM6001	MMP	MMP	0.0533	uM	7496.096	0.9639	0.9328	1.0771
MDA-MB-157	TNBC	Basal B	GM6001	MMP	MMP	0.267	uM	7496.096	0.9452	0.8980	1.0771
MDA-MB-157	TNBC	Basal B	GM6001	MMP	MMP	1.33	uM	7496.096	0.9659	0.9366	1.0771
MDA-MB-157	TNBC	Basal B	GM6001	MMP	MMP	6.67	uM	7496.096	0.9375	0.8836	1.0771

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)