Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
AU565	HER2amp	Luminal	Everolimus	MTOR	MTOR	2.67	uM	10880.156	0.5612	0.3707	1.5288
AU565	HER2amp	Luminal	Everolimus	MTOR	MTOR	13.3	uM	10880.156	0.5170	0.2991	1.5288
AU565	HER2amp	Luminal	Everolimus	MTOR	MTOR	66.7	uM	10880.156	0.0138	-0.8788	1.5288
BT-20	TNBC	Basal A	Everolimus	MTOR	MTOR	0.000171	uM	11854.156	1.0804	1.1469	1.0916
BT-20	TNBC	Basal A	Everolimus	MTOR	MTOR	0.000853	uM	11854.156	1.0546	1.0998	1.0916
BT-20	TNBC	Basal A	Everolimus	MTOR	MTOR	0.00427	uM	11854.156	1.0437	1.0800	1.0916
BT-20	TNBC	Basal A	Everolimus	MTOR	MTOR	0.0213	uM	11854.156	0.9509	0.9098	1.0916
BT-20	TNBC	Basal A	Everolimus	MTOR	MTOR	0.107	uM	11854.156	0.6788	0.4025	1.0916
BT-20	TNBC	Basal A	Everolimus	MTOR	MTOR	0.533	uM	11854.156	0.7111	0.4634	1.0916
BT-20	TNBC	Basal A	Everolimus	MTOR	MTOR	2.67	uM	11854.156	0.7384	0.5149	1.0916
BT-20	TNBC	Basal A	Everolimus	MTOR	MTOR	13.3	uM	11854.156	0.6902	0.4241	1.0916
BT-20	TNBC	Basal A	Everolimus	MTOR	MTOR	66.7	uM	11854.156	0.3313	-0.2730	1.0916
BT-474	HER2amp	Luminal	Everolimus	MTOR	MTOR	0.000171	uM	12056.164	0.9441	0.8804	0.9328
BT-474	HER2amp	Luminal	Everolimus	MTOR	MTOR	0.000853	uM	12056.164	0.8978	0.7817	0.9328
BT-474	HER2amp	Luminal	Everolimus	MTOR	MTOR	0.00427	uM	12056.164	0.8519	0.6842	0.9328
BT-474	HER2amp	Luminal	Everolimus	MTOR	MTOR	0.0213	uM	12056.164	0.7247	0.4162	0.9328
BT-474	HER2amp	Luminal	Everolimus	MTOR	MTOR	0.107	uM	12056.164	0.6068	0.1707	0.9328
BT-474	HER2amp	Luminal	Everolimus	MTOR	MTOR	0.533	uM	12056.164	0.6495	0.2592	0.9328
BT-474	HER2amp	Luminal	Everolimus	MTOR	MTOR	2.67	uM	12056.164	0.6320	0.2228	0.9328
BT-474	HER2amp	Luminal	Everolimus	MTOR	MTOR	13.3	uM	12056.164	0.5796	0.1146	0.9328
BT-474	HER2amp	Luminal	Everolimus	MTOR	MTOR	66.7	uM	12056.164	0.2994	-0.4510	0.9328
BT-474	HER2amp	Luminal	Everolimus	MTOR	MTOR	0.000171	uM	12178.164	1.0391	1.1401	0.5660
BT-474	HER2amp	Luminal	Everolimus	MTOR	MTOR	0.000853	uM	12178.164	1.0218	1.0776	0.5660
BT-474	HER2amp	Luminal	Everolimus	MTOR	MTOR	0.00427	uM	12178.164	0.8541	0.5136	0.5660
BT-474	HER2amp	Luminal	Everolimus	MTOR	MTOR	0.0213	uM	12178.164	0.8144	0.3915	0.5660
BT-474	HER2amp	Luminal	Everolimus	MTOR	MTOR	0.107	uM	12178.164	0.7709	0.2630	0.5660
BT-474	HER2amp	Luminal	Everolimus	MTOR	MTOR	0.533	uM	12178.164	0.7273	0.1395	0.5660
BT-474	HER2amp	Luminal	Everolimus	MTOR	MTOR	2.67	uM	12178.164	0.7440	0.1862	0.5660
BT-474	HER2amp	Luminal	Everolimus	MTOR	MTOR	13.3	uM	12178.164	0.7165	0.1098	0.5660
BT-474	HER2amp	Luminal	Everolimus	MTOR	MTOR	66.7	uM	12178.164	0.4408	-0.5296	0.5660
BT-474	HER2amp	Luminal	Everolimus	MTOR	MTOR	0.000171	uM	12291.156	0.9472	0.8248	0.5920
BT-474	HER2amp	Luminal	Everolimus	MTOR	MTOR	0.000853	uM	12291.156	0.8254	0.4462	0.5920
BT-474	HER2amp	Luminal	Everolimus	MTOR	MTOR	0.00427	uM	12291.156	0.8400	0.4899	0.5920
BT-474	HER2amp	Luminal	Everolimus	MTOR	MTOR	0.0213	uM	12291.156	0.7280	0.1700	0.5920
BT-474	HER2amp	Luminal	Everolimus	MTOR	MTOR	0.107	uM	12291.156	0.6372	-0.0659	0.5920
BT-474	HER2amp	Luminal	Everolimus	MTOR	MTOR	0.533	uM	12291.156	0.6636	0.0004	0.5920
BT-474	HER2amp	Luminal	Everolimus	MTOR	MTOR	2.67	uM	12291.156	0.5739	-0.2173	0.5920
BT-474	HER2amp	Luminal	Everolimus	MTOR	MTOR	13.3	uM	12291.156	0.5902	-0.1794	0.5920
BT-474	HER2amp	Luminal	Everolimus	MTOR	MTOR	66.7	uM	12291.156	0.4502	-0.4806	0.5920
BT-483	HR+	Luminal	Everolimus	MTOR	MTOR	0.000171	uM	11855.156	1.0141	1.0595	0.4788
BT-483	HR+	Luminal	Everolimus	MTOR	MTOR	0.000853	uM	11855.156	1.0322	1.1369	0.4788
BT-483	HR+	Luminal	Everolimus	MTOR	MTOR	0.00427	uM	11855.156	0.9274	0.7088	0.4788
BT-483	HR+	Luminal	Everolimus	MTOR	MTOR	0.0213	uM	11855.156	0.8314	0.3598	0.4788
BT-483	HR+	Luminal	Everolimus	MTOR	MTOR	0.107	uM	11855.156	0.7864	0.2107	0.4788
BT-483	HR+	Luminal	Everolimus	MTOR	MTOR	0.533	uM	11855.156	0.7913	0.2265	0.4788
BT-483	HR+	Luminal	Everolimus	MTOR	MTOR	2.67	uM	11855.156	0.8409	0.3927	0.4788
BT-483	HR+	Luminal	Everolimus	MTOR	MTOR	13.3	uM	11855.156	0.7517	0.1019	0.4788
BT-483	HR+	Luminal	Everolimus	MTOR	MTOR	66.7	uM	11855.156	0.2867	-0.8529	0.4788
BT-549	TNBC	Basal B	Everolimus	MTOR	MTOR	0.000171	uM	12305.156	0.9135	0.9389	2.9137
BT-549	TNBC	Basal B	Everolimus	MTOR	MTOR	0.000853	uM	12305.156	0.8695	0.9063	2.9137

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)