Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
184A1	NM	Basal	Docetaxel	TUBB	TUBB	2	uM	12684.002	0.6821	0.5562	1.5245
184A1	NM	Basal	Docetaxel	TUBB	TUBB	10	uM	12684.002	0.6698	0.5376	1.5245
184B5	NM	Basal	Docetaxel	TUBB	TUBB	0.0000256	uM	9095.002	1.0257	1.0484	1.0607
184B5	NM	Basal	Docetaxel	TUBB	TUBB	0.000128	uM	9095.002	1.0406	1.0765	1.0607
184B5	NM	Basal	Docetaxel	TUBB	TUBB	0.00064	uM	9095.002	0.9755	0.9537	1.0607
184B5	NM	Basal	Docetaxel	TUBB	TUBB	0.0032	uM	9095.002	0.7778	0.5782	1.0607
184B5	NM	Basal	Docetaxel	TUBB	TUBB	0.016	uM	9095.002	0.6832	0.3966	1.0607
184B5	NM	Basal	Docetaxel	TUBB	TUBB	0.08	uM	9095.002	0.6525	0.3373	1.0607
184B5	NM	Basal	Docetaxel	TUBB	TUBB	0.4	uM	9095.002	0.6297	0.2932	1.0607
184B5	NM	Basal	Docetaxel	TUBB	TUBB	2	uM	9095.002	0.7446	0.5146	1.0607
184B5	NM	Basal	Docetaxel	TUBB	TUBB	10	uM	9095.002	0.6938	0.4170	1.0607
184B5	NM	Basal	Docetaxel	TUBB	TUBB	0.0000256	uM	12979.002	0.8682	0.7966	1.3178
184B5	NM	Basal	Docetaxel	TUBB	TUBB	0.000128	uM	12979.002	1.2203	1.3261	1.3178
184B5	NM	Basal	Docetaxel	TUBB	TUBB	0.00064	uM	12979.002	0.8396	0.7515	1.3178
184B5	NM	Basal	Docetaxel	TUBB	TUBB	0.0032	uM	12979.002	1.0834	1.1254	1.3178
184B5	NM	Basal	Docetaxel	TUBB	TUBB	0.016	uM	12979.002	0.8258	0.7297	1.3178
184B5	NM	Basal	Docetaxel	TUBB	TUBB	0.08	uM	12979.002	0.8207	0.7215	1.3178
184B5	NM	Basal	Docetaxel	TUBB	TUBB	0.4	uM	12979.002	0.8483	0.7653	1.3178
184B5	NM	Basal	Docetaxel	TUBB	TUBB	2	uM	12979.002	0.8956	0.8395	1.3178
184B5	NM	Basal	Docetaxel	TUBB	TUBB	10	uM	12979.002	0.8210	0.7220	1.3178
600MPE	HR+	Luminal	Docetaxel	TUBB	TUBB	0.0000256	uM	9118.002	1.0333	1.0674	0.9880
600MPE	HR+	Luminal	Docetaxel	TUBB	TUBB	0.000128	uM	9118.002	1.1219	1.2468	0.9880
600MPE	HR+	Luminal	Docetaxel	TUBB	TUBB	0.00064	uM	9118.002	0.9861	0.9719	0.9880
600MPE	HR+	Luminal	Docetaxel	TUBB	TUBB	0.0032	uM	9118.002	0.9942	0.9882	0.9880
600MPE	HR+	Luminal	Docetaxel	TUBB	TUBB	0.016	uM	9118.002	0.9105	0.8190	0.9880
600MPE	HR+	Luminal	Docetaxel	TUBB	TUBB	0.08	uM	9118.002	0.7532	0.5012	0.9880
600MPE	HR+	Luminal	Docetaxel	TUBB	TUBB	0.4	uM	9118.002	0.6726	0.3388	0.9880
600MPE	HR+	Luminal	Docetaxel	TUBB	TUBB	2	uM	9118.002	0.7057	0.4055	0.9880
600MPE	HR+	Luminal	Docetaxel	TUBB	TUBB	10	uM	9118.002	0.8445	0.6855	0.9880
AU565	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.0000256	uM	7793.002	1.0110	1.0190	1.1545
AU565	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.000128	uM	7793.002	1.0271	1.0469	1.1545
AU565	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.00064	uM	7793.002	1.0237	1.0410	1.1545
AU565	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.0032	uM	7793.002	0.8583	0.7522	1.1545
AU565	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.016	uM	7793.002	0.1326	-0.6525	1.1545
AU565	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.08	uM	7793.002	0.0389	-0.8798	1.1545
AU565	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.4	uM	7793.002	0.0469	-0.8587	1.1545
AU565	HER2amp	Luminal	Docetaxel	TUBB	TUBB	2	uM	7793.002	0.0502	-0.8502	1.1545
AU565	HER2amp	Luminal	Docetaxel	TUBB	TUBB	10	uM	7793.002	0.0446	-0.8647	1.1545
AU565	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.0000256	uM	9146.002	1.0464	1.0732	1.2611
AU565	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.000128	uM	9146.002	1.0299	1.0473	1.2611
AU565	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.00064	uM	9146.002	1.0700	1.1102	1.2611
AU565	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.0032	uM	9146.002	0.9121	0.8593	1.2611
AU565	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.016	uM	9146.002	0.1267	-0.6113	1.2611
AU565	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.08	uM	9146.002	0.0955	-0.6895	1.2611
AU565	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.4	uM	9146.002	0.0882	-0.7085	1.2611
AU565	HER2amp	Luminal	Docetaxel	TUBB	TUBB	2	uM	9146.002	0.1018	-0.6733	1.2611
AU565	HER2amp	Luminal	Docetaxel	TUBB	TUBB	10	uM	9146.002	0.1168	-0.6357	1.2611
AU565	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.0000256	uM	13030.002	1.0656	1.2344	0.5732
AU565	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.000128	uM	13030.002	0.9694	0.8944	0.5732
AU565	HER2amp	Luminal	Docetaxel	TUBB	TUBB	0.00064	uM	13030.002	0.9423	0.8029	0.5732

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)