Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM229PE | TNBC | - | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13062.176 | 0.9640 | 0.9593 | 1.7805 | |
| SUM229PE | TNBC | - | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13062.176 | 0.9911 | 0.9900 | 1.7805 | |
| SUM229PE | TNBC | - | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13062.176 | 1.0070 | 1.0079 | 1.7805 | |
| SUM229PE | TNBC | - | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13062.176 | 0.9662 | 0.9617 | 1.7805 | |
| SUM229PE | TNBC | - | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13062.176 | 0.9763 | 0.9732 | 1.7805 | |
| SUM229PE | TNBC | - | Dichloroacetate | PDK | PDK | 0.133 | uM | 13062.176 | 0.9375 | 0.9288 | 1.7805 | |
| SUM229PE | TNBC | - | Dichloroacetate | PDK | PDK | 0.667 | uM | 13062.176 | 0.9935 | 0.9927 | 1.7805 | |
| SUM229PE | TNBC | - | Dichloroacetate | PDK | PDK | 3.33 | uM | 13062.176 | 0.9587 | 0.9532 | 1.7805 | |
| SUM52PE | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 12969.176 | 0.9670 | 0.9383 | 1.0709 | |
| SUM52PE | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 12969.176 | 1.0479 | 1.0893 | 1.0709 | |
| SUM52PE | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.000213 | uM | 12969.176 | 0.9698 | 0.9436 | 1.0709 | |
| SUM52PE | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00107 | uM | 12969.176 | 1.0385 | 1.0718 | 1.0709 | |
| SUM52PE | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00533 | uM | 12969.176 | 0.9825 | 0.9674 | 1.0709 | |
| SUM52PE | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.0267 | uM | 12969.176 | 0.8733 | 0.7623 | 1.0709 | |
| SUM52PE | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.133 | uM | 12969.176 | 0.9757 | 0.9546 | 1.0709 | |
| SUM52PE | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.667 | uM | 12969.176 | 0.9412 | 0.8900 | 1.0709 | |
| SUM52PE | HR+ | Luminal | Dichloroacetate | PDK | PDK | 3.33 | uM | 12969.176 | 1.0192 | 1.0358 | 1.0709 | |
| SUM52PE | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13570.176 | 0.9259 | 0.6559 | 0.4076 | |
| SUM52PE | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13570.176 | 0.9870 | 0.9368 | 0.4076 | |
| SUM52PE | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13570.176 | 0.9131 | 0.6000 | 0.4076 | |
| SUM52PE | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13570.176 | 0.9445 | 0.7384 | 0.4076 | |
| SUM52PE | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13570.176 | 0.9606 | 0.8122 | 0.4076 | |
| SUM52PE | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13570.176 | 0.8718 | 0.4284 | 0.4076 | |
| SUM52PE | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.133 | uM | 13570.176 | 0.9031 | 0.5574 | 0.4076 | |
| SUM52PE | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.667 | uM | 13570.176 | 0.9408 | 0.7219 | 0.4076 | |
| SUM52PE | HR+ | Luminal | Dichloroacetate | PDK | PDK | 3.33 | uM | 13570.176 | 0.9569 | 0.7949 | 0.4076 | |
| T47D | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 12720.176 | 0.9398 | 0.8732 | 0.9483 | |
| T47D | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 12720.176 | 0.9594 | 0.9144 | 0.9483 | |
| T47D | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.000213 | uM | 12720.176 | 0.9651 | 0.9266 | 0.9483 | |
| T47D | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00107 | uM | 12720.176 | 0.9945 | 0.9883 | 0.9483 | |
| T47D | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00533 | uM | 12720.176 | 0.9591 | 0.9137 | 0.9483 | |
| T47D | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.0267 | uM | 12720.176 | 0.9535 | 0.9021 | 0.9483 | |
| T47D | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.133 | uM | 12720.176 | 0.9657 | 0.9277 | 0.9483 | |
| T47D | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.667 | uM | 12720.176 | 0.9311 | 0.8550 | 0.9483 | |
| T47D | HR+ | Luminal | Dichloroacetate | PDK | PDK | 3.33 | uM | 12720.176 | 0.8878 | 0.7642 | 0.9483 | |
| T47DKBLUC | Unknown | Unknown | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13070.176 | 0.9812 | 0.9611 | 0.9664 | |
| T47DKBLUC | Unknown | Unknown | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13070.176 | 0.9474 | 0.8912 | 0.9664 | |
| T47DKBLUC | Unknown | Unknown | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13070.176 | 0.9672 | 0.9321 | 0.9664 | |
| T47DKBLUC | Unknown | Unknown | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13070.176 | 0.9978 | 0.9954 | 0.9664 | |
| T47DKBLUC | Unknown | Unknown | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13070.176 | 0.9798 | 0.9583 | 0.9664 | |
| T47DKBLUC | Unknown | Unknown | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13070.176 | 0.9409 | 0.8778 | 0.9664 | |
| T47DKBLUC | Unknown | Unknown | Dichloroacetate | PDK | PDK | 0.133 | uM | 13070.176 | 0.9249 | 0.8448 | 0.9664 | |
| T47DKBLUC | Unknown | Unknown | Dichloroacetate | PDK | PDK | 0.667 | uM | 13070.176 | 0.9600 | 0.9173 | 0.9664 | |
| T47DKBLUC | Unknown | Unknown | Dichloroacetate | PDK | PDK | 3.33 | uM | 13070.176 | 0.8856 | 0.7638 | 0.9664 | |
| UACC-812 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13078.176 | 0.9568 | 0.8808 | 0.7179 | |
| UACC-812 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13078.176 | 0.9331 | 0.8160 | 0.7179 | |
| UACC-812 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13078.176 | 0.9912 | 0.9754 | 0.7179 | |
| UACC-812 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13078.176 | 0.9840 | 0.9555 | 0.7179 | |
| UACC-812 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13078.176 | 0.9718 | 0.9219 | 0.7179 | |
| UACC-812 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13078.176 | 0.9590 | 0.8867 | 0.7179 |