Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13761.176 | 0.9542 | 0.7699 | 0.3832 | |
| SUM1315MO2 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.133 | uM | 13761.176 | 0.9573 | 0.7846 | 0.3832 | |
| SUM1315MO2 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.667 | uM | 13761.176 | 0.9855 | 0.9249 | 0.3832 | |
| SUM1315MO2 | TNBC | Basal B | Dichloroacetate | PDK | PDK | 3.33 | uM | 13761.176 | 0.9335 | 0.6711 | 0.3832 | |
| SUM149PT | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13123.176 | 0.8673 | 0.7576 | 1.1020 | |
| SUM149PT | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13123.176 | 0.9969 | 0.9945 | 1.1020 | |
| SUM149PT | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13123.176 | 0.9305 | 0.8735 | 1.1020 | |
| SUM149PT | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13123.176 | 0.8655 | 0.7543 | 1.1020 | |
| SUM149PT | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13123.176 | 0.9398 | 0.8905 | 1.1020 | |
| SUM149PT | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13123.176 | 0.8257 | 0.6809 | 1.1020 | |
| SUM149PT | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.133 | uM | 13123.176 | 0.9373 | 0.8859 | 1.1020 | |
| SUM149PT | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.667 | uM | 13123.176 | 0.8006 | 0.6345 | 1.1020 | |
| SUM149PT | TNBC | Basal B | Dichloroacetate | PDK | PDK | 3.33 | uM | 13123.176 | 0.8990 | 0.8158 | 1.1020 | |
| SUM159PT | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13004.176 | 0.9617 | 0.9773 | 3.4179 | |
| SUM159PT | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13004.176 | 1.0198 | 1.0115 | 3.4179 | |
| SUM159PT | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13004.176 | 1.0660 | 1.0378 | 3.4179 | |
| SUM159PT | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13004.176 | 0.9924 | 0.9955 | 3.4179 | |
| SUM159PT | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13004.176 | 1.0233 | 1.0135 | 3.4179 | |
| SUM159PT | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13004.176 | 0.9401 | 0.9642 | 3.4179 | |
| SUM159PT | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.133 | uM | 13004.176 | 0.9551 | 0.9733 | 3.4179 | |
| SUM159PT | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.667 | uM | 13004.176 | 0.9344 | 0.9607 | 3.4179 | |
| SUM159PT | TNBC | Basal B | Dichloroacetate | PDK | PDK | 3.33 | uM | 13004.176 | 0.9047 | 0.9422 | 3.4179 | |
| SUM159PT | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13054.176 | 0.9462 | 0.9659 | 3.2146 | |
| SUM159PT | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13054.176 | 1.0254 | 1.0156 | 3.2146 | |
| SUM159PT | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13054.176 | 0.9479 | 0.9670 | 3.2146 | |
| SUM159PT | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13054.176 | 1.0067 | 1.0042 | 3.2146 | |
| SUM159PT | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13054.176 | 1.0481 | 1.0294 | 3.2146 | |
| SUM159PT | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13054.176 | 0.8793 | 0.9216 | 3.2146 | |
| SUM159PT | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.133 | uM | 13054.176 | 1.0367 | 1.0226 | 3.2146 | |
| SUM159PT | TNBC | Basal B | Dichloroacetate | PDK | PDK | 0.667 | uM | 13054.176 | 0.9175 | 0.9471 | 3.2146 | |
| SUM159PT | TNBC | Basal B | Dichloroacetate | PDK | PDK | 3.33 | uM | 13054.176 | 0.8706 | 0.9156 | 3.2146 | |
| SUM185PE | TNBC | Luminal | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13140.176 | 0.9263 | 0.7828 | 0.6663 | |
| SUM185PE | TNBC | Luminal | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13140.176 | 0.9275 | 0.7863 | 0.6663 | |
| SUM185PE | TNBC | Luminal | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13140.176 | 0.9312 | 0.7970 | 0.6663 | |
| SUM185PE | TNBC | Luminal | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13140.176 | 0.9553 | 0.8673 | 0.6663 | |
| SUM185PE | TNBC | Luminal | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13140.176 | 0.9931 | 0.9792 | 0.6663 | |
| SUM185PE | TNBC | Luminal | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13140.176 | 0.9944 | 0.9832 | 0.6663 | |
| SUM185PE | TNBC | Luminal | Dichloroacetate | PDK | PDK | 0.133 | uM | 13140.176 | 1.0394 | 1.1195 | 0.6663 | |
| SUM185PE | TNBC | Luminal | Dichloroacetate | PDK | PDK | 0.667 | uM | 13140.176 | 1.0043 | 1.0128 | 0.6663 | |
| SUM185PE | TNBC | Luminal | Dichloroacetate | PDK | PDK | 3.33 | uM | 13140.176 | 0.9363 | 0.8118 | 0.6663 | |
| SUM229PE | TNBC | - | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13009.176 | 0.9571 | 0.9463 | 1.6112 | |
| SUM229PE | TNBC | - | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13009.176 | 1.0041 | 1.0051 | 1.6112 | |
| SUM229PE | TNBC | - | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13009.176 | 0.9993 | 0.9991 | 1.6112 | |
| SUM229PE | TNBC | - | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13009.176 | 1.0207 | 1.0255 | 1.6112 | |
| SUM229PE | TNBC | - | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13009.176 | 0.9755 | 0.9695 | 1.6112 | |
| SUM229PE | TNBC | - | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13009.176 | 0.9641 | 0.9551 | 1.6112 | |
| SUM229PE | TNBC | - | Dichloroacetate | PDK | PDK | 0.133 | uM | 13009.176 | 0.9616 | 0.9520 | 1.6112 | |
| SUM229PE | TNBC | - | Dichloroacetate | PDK | PDK | 0.667 | uM | 13009.176 | 0.9686 | 0.9608 | 1.6112 | |
| SUM229PE | TNBC | - | Dichloroacetate | PDK | PDK | 3.33 | uM | 13009.176 | 0.9553 | 0.9440 | 1.6112 | |
| SUM229PE | TNBC | - | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13062.176 | 0.9837 | 0.9816 | 1.7805 |