Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47DKBLUC | Unknown | Unknown | Erlotinib | EGFR | ErbB | 66.7 | uM | 7546.091 | 0.8326 | 0.6366 | 0.9137 | |
| UACC-812 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.0000853 | uM | 7547.092 | 0.9365 | 0.8714 | 0.9866 | |
| UACC-812 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.000427 | uM | 7547.092 | 0.8161 | 0.6276 | 0.9866 | |
| UACC-812 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.00213 | uM | 7547.092 | 0.9199 | 0.8376 | 0.9866 | |
| UACC-812 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.0107 | uM | 7547.092 | 0.9075 | 0.8126 | 0.9866 | |
| UACC-812 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.0533 | uM | 7547.092 | 0.9751 | 0.9495 | 0.9866 | |
| UACC-812 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.267 | uM | 7547.092 | 0.9242 | 0.8465 | 0.9866 | |
| UACC-812 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 1.33 | uM | 7547.092 | 0.8716 | 0.7399 | 0.9866 | |
| UACC-812 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 6.67 | uM | 7547.092 | 0.8400 | 0.6761 | 0.9866 | |
| UACC-812 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 33.3 | uM | 7547.092 | 0.5142 | 0.0191 | 0.9866 | |
| ZR-75-1 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7553.091 | 1.0480 | 1.0987 | 0.9738 | |
| ZR-75-1 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7553.091 | 1.0342 | 1.0703 | 0.9738 | |
| ZR-75-1 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7553.091 | 1.0057 | 1.0117 | 0.9738 | |
| ZR-75-1 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7553.091 | 1.0087 | 1.0179 | 0.9738 | |
| ZR-75-1 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.107 | uM | 7553.091 | 1.0231 | 1.0474 | 0.9738 | |
| ZR-75-1 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.533 | uM | 7553.091 | 1.0076 | 1.0156 | 0.9738 | |
| ZR-75-1 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 2.67 | uM | 7553.091 | 1.0447 | 1.0919 | 0.9738 | |
| ZR-75-1 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 13.3 | uM | 7553.091 | 0.9912 | 0.9820 | 0.9738 | |
| ZR-75-1 | HR+ | Luminal | Erlotinib | EGFR | ErbB | 66.7 | uM | 7553.091 | 0.9837 | 0.9665 | 0.9738 | |
| ZR75B | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7555.091 | 1.0886 | 1.1088 | 1.6040 | |
| ZR75B | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7555.091 | 1.0199 | 1.0248 | 1.6040 | |
| ZR75B | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7555.091 | 1.0381 | 1.0472 | 1.6040 | |
| ZR75B | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7555.091 | 0.9968 | 0.9960 | 1.6040 | |
| ZR75B | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.107 | uM | 7555.091 | 1.0207 | 1.0257 | 1.6040 | |
| ZR75B | HR+ | Luminal | Erlotinib | EGFR | ErbB | 0.533 | uM | 7555.091 | 0.9630 | 0.9535 | 1.6040 |