Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MX1 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 2.67 | uM | 7523.091 | 0.8529 | 0.6849 | 0.9283 | |
| MX1 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 13.3 | uM | 7523.091 | 0.6825 | 0.3253 | 0.9283 | |
| MX1 | Unknown | Unknown | Erlotinib | EGFR | ErbB | 66.7 | uM | 7523.091 | 0.3955 | -0.2637 | 0.9283 | |
| SK-BR-3 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7526.091 | 0.9179 | 0.9000 | 1.6709 | |
| SK-BR-3 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7526.091 | 0.9393 | 0.9265 | 1.6709 | |
| SK-BR-3 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7526.091 | 0.9182 | 0.9004 | 1.6709 | |
| SK-BR-3 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7526.091 | 0.9804 | 0.9765 | 1.6709 | |
| SK-BR-3 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.107 | uM | 7526.091 | 0.9070 | 0.8865 | 1.6709 | |
| SK-BR-3 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.533 | uM | 7526.091 | 0.9327 | 0.9183 | 1.6709 | |
| SK-BR-3 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 2.67 | uM | 7526.091 | 0.9180 | 0.9002 | 1.6709 | |
| SK-BR-3 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 13.3 | uM | 7526.091 | 0.6634 | 0.5645 | 1.6709 | |
| SK-BR-3 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 66.7 | uM | 7526.091 | 0.3046 | -0.0181 | 1.6709 | |
| SK-BR-3 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.0000853 | uM | 7527.092 | 1.0118 | 1.0116 | 2.0383 | |
| SK-BR-3 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.000427 | uM | 7527.092 | 0.9871 | 0.9873 | 2.0383 | |
| SK-BR-3 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.00213 | uM | 7527.092 | 0.9808 | 0.9811 | 2.0383 | |
| SK-BR-3 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.0107 | uM | 7527.092 | 0.9660 | 0.9664 | 2.0383 | |
| SK-BR-3 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.0533 | uM | 7527.092 | 0.9897 | 0.9899 | 2.0383 | |
| SK-BR-3 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 0.267 | uM | 7527.092 | 0.9570 | 0.9574 | 2.0383 | |
| SK-BR-3 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 1.33 | uM | 7527.092 | 0.9223 | 0.9222 | 2.0383 | |
| SK-BR-3 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 6.67 | uM | 7527.092 | 0.8752 | 0.8734 | 2.0383 | |
| SK-BR-3 | HER2amp | Luminal | Erlotinib | EGFR | ErbB | 33.3 | uM | 7527.092 | 0.3713 | 0.2300 | 2.0383 | |
| SUM1315MO2 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.000171 | uM | 7528.091 | 0.9593 | 0.9137 | 0.9421 | |
| SUM1315MO2 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.000853 | uM | 7528.091 | 0.9461 | 0.8857 | 0.9421 | |
| SUM1315MO2 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.00427 | uM | 7528.091 | 0.9810 | 0.9597 | 0.9421 | |
| SUM1315MO2 | TNBC | Basal B | Erlotinib | EGFR | ErbB | 0.0213 | uM | 7528.091 | 0.9895 | 0.9776 | 0.9421 |