Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AU565 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7794.017 | 1.0783 | 1.0774 | 1.9851 | |
| AU565 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7794.017 | 1.0362 | 1.0362 | 1.9851 | |
| AU565 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.011 | uM | 7794.017 | 1.1392 | 1.1357 | 1.9851 | |
| AU565 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7794.017 | 0.8811 | 0.8765 | 1.9851 | |
| AU565 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.276 | uM | 7794.017 | 0.2831 | 0.0591 | 1.9851 | |
| AU565 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 1.38 | uM | 7794.017 | 0.0948 | -0.3897 | 1.9851 | |
| AU565 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 6.9 | uM | 7794.017 | 0.0101 | -0.8029 | 1.9851 | |
| AU565 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 34.5 | uM | 7794.017 | 0.0079 | -0.8249 | 1.9851 | |
| AU565 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 172 | uM | 7794.017 | 0.0007 | -0.9484 | 1.9851 | |
| AU565 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.000441 | uM | 9035.017 | 0.7223 | 0.7352 | 2.2905 | |
| AU565 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.00221 | uM | 9035.017 | 0.9734 | 0.9766 | 2.2905 | |
| AU565 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.011 | uM | 9035.017 | 0.9866 | 0.9882 | 2.2905 | |
| AU565 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.0552 | uM | 9035.017 | 0.9194 | 0.9279 | 2.2905 | |
| AU565 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.276 | uM | 9035.017 | 0.2600 | 0.1108 | 2.2905 | |
| AU565 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 1.38 | uM | 9035.017 | 0.0972 | -0.2772 | 2.2905 | |
| AU565 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 6.9 | uM | 9035.017 | 0.0025 | -0.8530 | 2.2905 | |
| AU565 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 34.5 | uM | 9035.017 | 0.0016 | -0.8793 | 2.2905 | |
| AU565 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 172 | uM | 9035.017 | 0.8214 | 0.8354 | 2.2905 | |
| BT-474 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7798.017 | 0.9462 | 0.9234 | 1.4161 | |
| BT-474 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7798.017 | 1.0388 | 1.0545 | 1.4161 | |
| BT-474 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.011 | uM | 7798.017 | 1.0146 | 1.0206 | 1.4161 | |
| BT-474 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7798.017 | 1.0085 | 1.0120 | 1.4161 | |
| BT-474 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 0.276 | uM | 7798.017 | 0.9589 | 0.9416 | 1.4161 | |
| BT-474 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 1.38 | uM | 7798.017 | 0.4615 | 0.1584 | 1.4161 | |
| BT-474 | HER2amp | Luminal | Epirubicin | TOP2 | TOP | 6.9 | uM | 7798.017 | 0.7829 | 0.6825 | 1.4161 |