Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HMT-3522 S1 | Unknown | Unknown | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7911.05 | 1.0249 | 1.0276 | 1.7938 | |
| HMT-3522 S1 | Unknown | Unknown | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7911.05 | 0.3851 | 0.1749 | 1.7938 | |
| HMT-3522 S1 | Unknown | Unknown | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7911.05 | 0.4076 | 0.2126 | 1.7938 | |
| HMT-3522 S1 | Unknown | Unknown | 17-AAG | HSP90 | HSP90 | 4 | uM | 7911.05 | 0.3947 | 0.1911 | 1.7938 | |
| HMT-3522 S1 | Unknown | Unknown | 17-AAG | HSP90 | HSP90 | 20 | uM | 7911.05 | 0.3560 | 0.1245 | 1.7938 | |
| HMT-3522 S1 | Unknown | Unknown | 17-AAG | HSP90 | HSP90 | 100 | uM | 7911.05 | 0.2845 | -0.0075 | 1.7938 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7862.04 | 0.9277 | 0.8995 | 1.4556 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7862.04 | 1.0023 | 1.0032 | 1.4556 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7862.04 | 0.9759 | 0.9668 | 1.4556 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7862.04 | 0.9773 | 0.9687 | 1.4556 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7862.04 | 0.4668 | 0.1850 | 1.4556 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7862.04 | 0.1827 | -0.3780 | 1.4556 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 4 | uM | 7862.04 | 0.1507 | -0.4551 | 1.4556 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 20 | uM | 7862.04 | 0.1963 | -0.3465 | 1.4556 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 100 | uM | 7862.04 | 0.0648 | -0.6949 | 1.4556 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7863.05 | 1.0361 | 1.0425 | 1.6873 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7863.05 | 1.0307 | 1.0362 | 1.6873 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7863.05 | 1.0577 | 1.0676 | 1.6873 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7863.05 | 0.9640 | 0.9570 | 1.6873 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7863.05 | 0.3313 | 0.0391 | 1.6873 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7863.05 | 0.1707 | -0.2986 | 1.6873 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 4 | uM | 7863.05 | 0.1869 | -0.2598 | 1.6873 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 20 | uM | 7863.05 | 0.2169 | -0.1917 | 1.6873 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 100 | uM | 7863.05 | 0.0600 | -0.6226 | 1.6873 | |
| Hs 578T | TNBC | Basal B | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7864.037 | 0.9983 | 0.9981 | 1.7830 |