Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7829.017 | 0.9511 | 0.9494 | 1.9566 | |
| HCC1806 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7829.017 | 0.6437 | 0.5967 | 1.9566 | |
| HCC1806 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7829.017 | 0.1736 | -0.1828 | 1.9566 | |
| HCC1806 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7829.017 | 0.0063 | -0.8505 | 1.9566 | |
| HCC1806 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7829.017 | 0.9563 | 0.9548 | 1.9566 | |
| HCC1806 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7830.017 | 1.1005 | 1.1142 | 1.7247 | |
| HCC1806 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7830.017 | 0.9098 | 0.8934 | 1.7247 | |
| HCC1806 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7830.017 | 0.9575 | 0.9503 | 1.7247 | |
| HCC1806 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7830.017 | 0.8812 | 0.8586 | 1.7247 | |
| HCC1806 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7830.017 | 0.9680 | 0.9626 | 1.7247 | |
| HCC1806 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7830.017 | 0.6259 | 0.5242 | 1.7247 | |
| HCC1806 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7830.017 | 0.2080 | -0.1954 | 1.7247 | |
| HCC1806 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7830.017 | 0.0200 | -0.7927 | 1.7247 | |
| HCC1806 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7830.017 | 0.0141 | -0.8307 | 1.7247 | |
| HCC1806 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00128 | uM | 9376.049 | 0.9783 | 0.9773 | 1.9229 | |
| HCC1806 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0064 | uM | 9376.049 | 0.9103 | 0.9046 | 1.9229 | |
| HCC1806 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.032 | uM | 9376.049 | 1.0070 | 1.0073 | 1.9229 | |
| HCC1806 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.16 | uM | 9376.049 | 0.9067 | 0.9006 | 1.9229 | |
| HCC1806 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.8 | uM | 9376.049 | 0.9891 | 0.9886 | 1.9229 | |
| HCC1806 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 4 | uM | 9376.049 | 1.0151 | 1.0156 | 1.9229 | |
| HCC1806 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 20 | uM | 9376.049 | 0.9973 | 0.9972 | 1.9229 | |
| HCC1806 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 100 | uM | 9376.049 | 1.0399 | 1.0411 | 1.9229 | |
| HCC1806 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 500 | uM | 9376.049 | 0.9548 | 0.9525 | 1.9229 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7832.017 | 0.9950 | 0.9925 | 1.3404 | |
| HCC1937 | TNBC | Basal A | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7832.017 | 1.0274 | 1.0407 | 1.3404 |