Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1937 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7832.011 | 0.9434 | 0.9207 | 1.4385 | |
| HCC1937 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7832.011 | 0.9728 | 0.9620 | 1.4385 | |
| HCC1937 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 7832.011 | 0.9968 | 0.9955 | 1.4385 | |
| HCC1937 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7832.011 | 0.8629 | 0.8051 | 1.4385 | |
| HCC1937 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7832.011 | 0.5957 | 0.3952 | 1.4385 | |
| HCC1937 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7832.011 | 0.0898 | -0.6257 | 1.4385 | |
| HCC1937 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7832.011 | 0.0335 | -0.8114 | 1.4385 | |
| HCC1937 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7834.075 | 1.0085 | 1.0084 | 2.0182 | |
| HCC1937 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7834.075 | 1.0128 | 1.0126 | 2.0182 | |
| HCC1937 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7834.075 | 0.9619 | 0.9618 | 2.0182 | |
| HCC1937 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7834.075 | 1.0165 | 1.0162 | 2.0182 | |
| HCC1937 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 7834.075 | 0.9837 | 0.9838 | 2.0182 | |
| HCC1937 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7834.075 | 0.8859 | 0.8834 | 2.0182 | |
| HCC1937 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7834.075 | 0.4547 | 0.3534 | 2.0182 | |
| HCC1937 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7834.075 | 0.1351 | -0.2581 | 2.0182 | |
| HCC1937 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7834.075 | 0.0372 | -0.6087 | 2.0182 | |
| HCC1937 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 10262.021 | 1.0372 | 1.1103 | 0.6806 | |
| HCC1937 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 10262.021 | 1.0764 | 1.2285 | 0.6806 | |
| HCC1937 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 10262.021 | 1.0455 | 1.1350 | 0.6806 | |
| HCC1937 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 10262.021 | 1.0235 | 1.0693 | 0.6806 | |
| HCC1937 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 10262.021 | 0.9882 | 0.9655 | 0.6806 | |
| HCC1937 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 10262.021 | 1.0549 | 1.1632 | 0.6806 | |
| HCC1937 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 10262.021 | 0.6078 | -0.0376 | 0.6806 | |
| HCC1937 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 10262.021 | 0.2362 | -0.7601 | 0.6806 | |
| HCC1937 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 10262.021 | 0.0791 | -0.9519 | 0.6806 |