Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7820.011 | 0.0989 | -0.9365 | 0.6709 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9278.011 | 0.9902 | 0.9642 | 0.5434 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9278.011 | 1.0097 | 1.0359 | 0.5434 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9278.011 | 1.0016 | 1.0059 | 0.5434 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9278.011 | 1.0170 | 1.0628 | 0.5434 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 9278.011 | 1.0288 | 1.1072 | 0.5434 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9278.011 | 1.0096 | 1.0353 | 0.5434 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9278.011 | 0.8669 | 0.5378 | 0.5434 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9278.011 | 0.3743 | -0.6721 | 0.5434 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9278.011 | 0.0981 | -0.9721 | 0.5434 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 10019.12 | 0.9975 | 0.9898 | 0.4898 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 10019.12 | 1.0032 | 1.0133 | 0.4898 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 10019.12 | 1.0048 | 1.0194 | 0.4898 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 10019.12 | 1.0291 | 1.1205 | 0.4898 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 10019.12 | 1.1011 | 1.4345 | 0.4898 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 10019.12 | 1.0151 | 1.0621 | 0.4898 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 10019.12 | 0.8125 | 0.3090 | 0.4898 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 10019.12 | 0.3662 | -0.7428 | 0.4898 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 10019.12 | 0.0687 | -0.9916 | 0.4898 | |
| HCC1428 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9294.011 | 0.9746 | 0.9303 | 0.7255 | |
| HCC1428 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9294.011 | 1.0058 | 1.0160 | 0.7255 | |
| HCC1428 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9294.011 | 1.0085 | 1.0236 | 0.7255 | |
| HCC1428 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9294.011 | 1.0110 | 1.0303 | 0.7255 | |
| HCC1428 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 9294.011 | 1.0114 | 1.0316 | 0.7255 | |
| HCC1428 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9294.011 | 0.9867 | 0.9634 | 0.7255 |