Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | Bosutinib | Src | nRTK | 100 | uM | 10578.145 | 0.0196 | -0.8086 | 1.6766 | |
| HCC38 | TNBC | Basal B | Bosutinib | Src | nRTK | 0.000256 | uM | 11850.145 | 0.9344 | 0.9378 | 2.1492 | |
| HCC38 | TNBC | Basal B | Bosutinib | Src | nRTK | 0.00128 | uM | 11850.145 | 0.9430 | 0.9461 | 2.1492 | |
| HCC38 | TNBC | Basal B | Bosutinib | Src | nRTK | 0.0064 | uM | 11850.145 | 0.9372 | 0.9405 | 2.1492 | |
| HCC38 | TNBC | Basal B | Bosutinib | Src | nRTK | 0.032 | uM | 11850.145 | 0.9094 | 0.9136 | 2.1492 | |
| HCC38 | TNBC | Basal B | Bosutinib | Src | nRTK | 0.16 | uM | 11850.145 | 0.9929 | 0.9934 | 2.1492 | |
| HCC38 | TNBC | Basal B | Bosutinib | Src | nRTK | 0.8 | uM | 11850.145 | 0.7535 | 0.7533 | 2.1492 | |
| HCC38 | TNBC | Basal B | Bosutinib | Src | nRTK | 4 | uM | 11850.145 | 0.0392 | -0.5567 | 2.1492 | |
| HCC38 | TNBC | Basal B | Bosutinib | Src | nRTK | 20 | uM | 11850.145 | 0.0209 | -0.6694 | 2.1492 | |
| HCC38 | TNBC | Basal B | Bosutinib | Src | nRTK | 100 | uM | 11850.145 | 0.0129 | -0.7354 | 2.1492 | |
| HCC70 | TNBC | Basal A | Bosutinib | Src | nRTK | 0.000256 | uM | 10873.145 | 0.9818 | 0.9707 | 1.2454 | |
| HCC70 | TNBC | Basal A | Bosutinib | Src | nRTK | 0.00128 | uM | 10873.145 | 1.0112 | 1.0180 | 1.2454 | |
| HCC70 | TNBC | Basal A | Bosutinib | Src | nRTK | 0.0064 | uM | 10873.145 | 0.9958 | 0.9932 | 1.2454 | |
| HCC70 | TNBC | Basal A | Bosutinib | Src | nRTK | 0.032 | uM | 10873.145 | 1.0103 | 1.0165 | 1.2454 | |
| HCC70 | TNBC | Basal A | Bosutinib | Src | nRTK | 0.16 | uM | 10873.145 | 0.9796 | 0.9671 | 1.2454 | |
| HCC70 | TNBC | Basal A | Bosutinib | Src | nRTK | 0.8 | uM | 10873.145 | 0.7401 | 0.5707 | 1.2454 | |
| HCC70 | TNBC | Basal A | Bosutinib | Src | nRTK | 4 | uM | 10873.145 | 0.3151 | -0.2087 | 1.2454 | |
| HCC70 | TNBC | Basal A | Bosutinib | Src | nRTK | 20 | uM | 10873.145 | 0.1249 | -0.6236 | 1.2454 | |
| HCC70 | TNBC | Basal A | Bosutinib | Src | nRTK | 100 | uM | 10873.145 | 0.0270 | -0.8901 | 1.2454 | |
| HCC70 | TNBC | Basal A | Bosutinib | Src | nRTK | 0.0000853 | uM | 12400.17 | 0.9693 | 0.9487 | 1.1992 | |
| HCC70 | TNBC | Basal A | Bosutinib | Src | nRTK | 0.000427 | uM | 12400.17 | 1.0205 | 1.0341 | 1.1992 | |
| HCC70 | TNBC | Basal A | Bosutinib | Src | nRTK | 0.00213 | uM | 12400.17 | 0.9792 | 0.9653 | 1.1992 | |
| HCC70 | TNBC | Basal A | Bosutinib | Src | nRTK | 0.0107 | uM | 12400.17 | 0.9981 | 0.9969 | 1.1992 | |
| HCC70 | TNBC | Basal A | Bosutinib | Src | nRTK | 0.0533 | uM | 12400.17 | 0.9693 | 0.9487 | 1.1992 | |
| HCC70 | TNBC | Basal A | Bosutinib | Src | nRTK | 0.267 | uM | 12400.17 | 0.9450 | 0.9078 | 1.1992 |