Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14807.203 | 0.0394 | -0.6965 | 1.7148 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14807.203 | 0.0394 | -0.6965 | 1.7148 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14807.203 | 0.0227 | -0.7798 | 1.7148 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14807.203 | 0.0227 | -0.7798 | 1.7148 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 15338.203 | 0.9572 | 0.9546 | 1.9034 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 15338.203 | 0.9572 | 0.9546 | 1.9034 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 15338.203 | 0.8529 | 0.8396 | 1.9034 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 15338.203 | 0.8529 | 0.8396 | 1.9034 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 15338.203 | 0.3639 | 0.1760 | 1.9034 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 15338.203 | 0.3639 | 0.1760 | 1.9034 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 15338.203 | 0.0848 | -0.4528 | 1.9034 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 15338.203 | 0.0848 | -0.4528 | 1.9034 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 15338.203 | 0.0484 | -0.5926 | 1.9034 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 15338.203 | 0.0484 | -0.5926 | 1.9034 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 15338.203 | 0.0304 | -0.6809 | 1.9034 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 15338.203 | 0.0304 | -0.6809 | 1.9034 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 15338.203 | 0.0154 | -0.7769 | 1.9034 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 15338.203 | 0.0154 | -0.7769 | 1.9034 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 15338.203 | 0.0213 | -0.7351 | 1.9034 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 15338.203 | 0.0213 | -0.7351 | 1.9034 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 15338.203 | 0.0261 | -0.7052 | 1.9034 | |
| SUM229PE | TNBC | - | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 15338.203 | 0.0261 | -0.7052 | 1.9034 | |
| SUM52PE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7541.074 | 1.0771 | 1.1156 | 1.3223 | |
| SUM52PE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7541.074 | 1.0771 | 1.1156 | 1.3223 | |
| SUM52PE | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7541.074 | 0.9995 | 0.9992 | 1.3223 |