Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7467.074 | 0.0150 | -0.9315 | 1.2457 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7467.074 | 0.0150 | -0.9315 | 1.2457 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7467.074 | 0.0046 | -0.9732 | 1.2457 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7467.074 | 0.0046 | -0.9732 | 1.2457 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7467.074 | 0.0073 | -0.9614 | 1.2457 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7467.074 | 0.0073 | -0.9614 | 1.2457 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 167 | uM | 7467.074 | 0.0061 | -0.9666 | 1.2457 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 167 | uM | 7467.074 | 0.0061 | -0.9666 | 1.2457 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14906.203 | 0.9933 | 0.9830 | 0.7818 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14906.203 | 0.9933 | 0.9830 | 0.7818 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14906.203 | 0.9682 | 0.9191 | 0.7818 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14906.203 | 0.9682 | 0.9191 | 0.7818 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14906.203 | 0.8561 | 0.6395 | 0.7818 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14906.203 | 0.8561 | 0.6395 | 0.7818 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14906.203 | 0.0461 | -0.9610 | 0.7818 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14906.203 | 0.0461 | -0.9610 | 0.7818 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14906.203 | 0.0200 | -0.9866 | 0.7818 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14906.203 | 0.0200 | -0.9866 | 0.7818 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14906.203 | 0.0211 | -0.9857 | 0.7818 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14906.203 | 0.0211 | -0.9857 | 0.7818 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14906.203 | 0.0163 | -0.9897 | 0.7818 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14906.203 | 0.0163 | -0.9897 | 0.7818 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14906.203 | 0.0190 | -0.9875 | 0.7818 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14906.203 | 0.0190 | -0.9875 | 0.7818 | |
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14906.203 | 0.0217 | -0.9851 | 0.7818 |