Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7451.074 | 1.0095 | 1.0087 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7451.074 | 0.9454 | 0.9491 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7451.074 | 0.9454 | 0.9491 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7451.074 | 0.9489 | 0.9525 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7451.074 | 0.9489 | 0.9525 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7451.074 | 0.9139 | 0.9191 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7451.074 | 0.9139 | 0.9191 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7451.074 | 0.2394 | 0.0380 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7451.074 | 0.2394 | 0.0380 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7451.074 | 0.0199 | -0.6681 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7451.074 | 0.0199 | -0.6681 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7451.074 | 0.0088 | -0.7720 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7451.074 | 0.0088 | -0.7720 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7451.074 | 0.0081 | -0.7800 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7451.074 | 0.0081 | -0.7800 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 167 | uM | 7451.074 | 0.0063 | -0.8044 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 167 | uM | 7451.074 | 0.0063 | -0.8044 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14731.203 | 0.9653 | 0.9693 | 2.2762 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14731.203 | 0.9653 | 0.9693 | 2.2762 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14731.203 | 0.9462 | 0.9520 | 2.2762 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14731.203 | 0.9462 | 0.9520 | 2.2762 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14731.203 | 0.9446 | 0.9505 | 2.2762 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14731.203 | 0.9446 | 0.9505 | 2.2762 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14731.203 | 0.6464 | 0.6511 | 2.2762 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14731.203 | 0.6464 | 0.6511 | 2.2762 |