Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7907.016 | 1.0595 | 1.0899 | 1.3145 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7907.016 | 0.8274 | 0.7316 | 1.3145 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7907.016 | 0.8595 | 0.7824 | 1.3145 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7907.016 | 0.9382 | 0.9052 | 1.3145 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7907.016 | 0.7327 | 0.5786 | 1.3145 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7909.016 | 1.1756 | 1.2506 | 1.3701 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7909.016 | 0.8119 | 0.7178 | 1.3701 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7909.016 | 1.1808 | 1.2579 | 1.3701 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7909.016 | 0.9572 | 0.9371 | 1.3701 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7909.016 | 1.1520 | 1.2175 | 1.3701 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7909.016 | 0.8519 | 0.7792 | 1.3701 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7909.016 | 0.8949 | 0.8443 | 1.3701 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7909.016 | 0.9425 | 0.9154 | 1.3701 | ||
| MDA-MB-468 | TNBC | Basal A | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7909.016 | 0.5292 | 0.2570 | 1.3701 | ||
| SK-BR-3 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7912.016 | 0.9792 | 0.9053 | 0.4337 | ||
| SK-BR-3 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7912.016 | 0.9707 | 0.8673 | 0.4337 | ||
| SK-BR-3 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7912.016 | 0.9756 | 0.8892 | 0.4337 | ||
| SK-BR-3 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7912.016 | 0.9676 | 0.8537 | 0.4337 | ||
| SK-BR-3 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7912.016 | 0.9518 | 0.7849 | 0.4337 | ||
| SK-BR-3 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7912.016 | 0.8738 | 0.4654 | 0.4337 | ||
| SK-BR-3 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7912.016 | 0.8510 | 0.3787 | 0.4337 | ||
| SK-BR-3 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7912.016 | 0.8465 | 0.3618 | 0.4337 | ||
| SK-BR-3 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7912.016 | 0.8200 | 0.2656 | 0.4337 | ||
| SK-BR-3 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7914.016 | 0.9208 | 0.9009 | 1.6240 | ||
| SK-BR-3 | HER2amp | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7914.016 | 0.8952 | 0.8682 | 1.6240 |