Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184B5 | NM | Basal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 5896.074 | 0.7835 | 0.6826 | 1.4124 | |
| 184B5 | NM | Basal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 5896.074 | 0.2715 | -0.2054 | 1.4124 | |
| 184B5 | NM | Basal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 5896.074 | 0.2715 | -0.2054 | 1.4124 | |
| 184B5 | NM | Basal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 5896.074 | 0.1405 | -0.5017 | 1.4124 | |
| 184B5 | NM | Basal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 5896.074 | 0.1405 | -0.5017 | 1.4124 | |
| 184B5 | NM | Basal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 5896.074 | 0.0884 | -0.6411 | 1.4124 | |
| 184B5 | NM | Basal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 5896.074 | 0.0884 | -0.6411 | 1.4124 | |
| 184B5 | NM | Basal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 5896.074 | 0.0488 | -0.7643 | 1.4124 | |
| 184B5 | NM | Basal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 5896.074 | 0.0488 | -0.7643 | 1.4124 | |
| 184B5 | NM | Basal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 5896.074 | 0.0392 | -0.7981 | 1.4124 | |
| 184B5 | NM | Basal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 5896.074 | 0.0392 | -0.7981 | 1.4124 | |
| 184B5 | NM | Basal | Bortezomib | Proteasome | Proteasome | 167 | uM | 5896.074 | 0.0389 | -0.7992 | 1.4124 | |
| 184B5 | NM | Basal | Bortezomib | Proteasome | Proteasome | 167 | uM | 5896.074 | 0.0389 | -0.7992 | 1.4124 | |
| 184B5 | NM | Basal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 5897.074 | 0.9765 | 0.9633 | 1.2824 | |
| 184B5 | NM | Basal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 5897.074 | 0.9765 | 0.9633 | 1.2824 | |
| 184B5 | NM | Basal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 5897.074 | 0.9662 | 0.9470 | 1.2824 | |
| 184B5 | NM | Basal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 5897.074 | 0.9662 | 0.9470 | 1.2824 | |
| 184B5 | NM | Basal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 5897.074 | 0.9734 | 0.9584 | 1.2824 | |
| 184B5 | NM | Basal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 5897.074 | 0.9734 | 0.9584 | 1.2824 | |
| 184B5 | NM | Basal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 5897.074 | 0.3303 | -0.1569 | 1.2824 | |
| 184B5 | NM | Basal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 5897.074 | 0.3303 | -0.1569 | 1.2824 | |
| 184B5 | NM | Basal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 5897.074 | 0.2353 | -0.3529 | 1.2824 | |
| 184B5 | NM | Basal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 5897.074 | 0.2353 | -0.3529 | 1.2824 | |
| 184B5 | NM | Basal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 5897.074 | 0.1696 | -0.4986 | 1.2824 | |
| 184B5 | NM | Basal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 5897.074 | 0.1696 | -0.4986 | 1.2824 |