Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10643.072 | 1.0317 | 1.1046 | 0.6128 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10643.072 | 1.0280 | 1.0921 | 0.6128 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10643.072 | 0.7164 | 0.1605 | 0.6128 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10999.072 | 1.0577 | 1.1541 | 0.7551 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10999.072 | 0.9603 | 0.8955 | 0.7551 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10999.072 | 1.0103 | 1.0274 | 0.7551 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10999.072 | 0.9748 | 0.9337 | 0.7551 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10999.072 | 1.0188 | 1.0501 | 0.7551 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10999.072 | 0.9902 | 0.9741 | 0.7551 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10999.072 | 0.9764 | 0.9377 | 0.7551 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10999.072 | 1.0677 | 1.1812 | 0.7551 | |
| MDA-MB-361 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10999.072 | 0.9740 | 0.9315 | 0.7551 | |
| MDA-MB-415 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7511.073 | 1.0422 | 1.0772 | 1.0909 | |
| MDA-MB-415 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7511.073 | 0.9894 | 0.9806 | 1.0909 | |
| MDA-MB-415 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7511.073 | 1.0332 | 1.0608 | 1.0909 | |
| MDA-MB-415 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7511.073 | 1.0022 | 1.0041 | 1.0909 | |
| MDA-MB-415 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7511.073 | 0.9945 | 0.9899 | 1.0909 | |
| MDA-MB-415 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7511.073 | 1.0075 | 1.0138 | 1.0909 | |
| MDA-MB-415 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7511.073 | 1.0581 | 1.1063 | 1.0909 | |
| MDA-MB-415 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7511.073 | 0.9808 | 0.9648 | 1.0909 | |
| MDA-MB-415 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7511.073 | 0.8003 | 0.6306 | 1.0909 | |
| MDA-MB-415 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10938.072 | 1.2777 | 2.0952 | 0.5611 | |
| MDA-MB-415 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10938.072 | 1.2320 | 1.9008 | 0.5611 | |
| MDA-MB-415 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10938.072 | 1.3593 | 2.4565 | 0.5611 | |
| MDA-MB-415 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10938.072 | 1.4364 | 2.8134 | 0.5611 |