Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7830.018 | 0.1932 | -0.3161 | 1.5320 | |
| HCC1806 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7830.018 | 0.2483 | -0.1945 | 1.5320 | |
| HCC1806 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7830.018 | 0.3044 | -0.0798 | 1.5320 | |
| HCC1806 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7830.018 | 0.3262 | -0.0373 | 1.5320 | |
| HCC1806 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7830.018 | 0.2976 | -0.0933 | 1.5320 | |
| HCC1937 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7832.042 | 1.0153 | 1.0238 | 1.2810 | |
| HCC1937 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7832.042 | 0.9310 | 0.8915 | 1.2810 | |
| HCC1937 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7832.042 | 0.8551 | 0.7700 | 1.2810 | |
| HCC1937 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7832.042 | 0.6973 | 0.5094 | 1.2810 | |
| HCC1937 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7832.042 | 0.7181 | 0.5444 | 1.2810 | |
| HCC1937 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7832.042 | 0.7697 | 0.6304 | 1.2810 | |
| HCC1937 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7832.042 | 0.6922 | 0.5007 | 1.2810 | |
| HCC1937 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7832.042 | 0.6277 | 0.3904 | 1.2810 | |
| HCC1937 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7832.042 | 0.0186 | -0.9109 | 1.2810 | |
| HCC1937 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7833.042 | 0.9516 | 0.9063 | 1.0332 | |
| HCC1937 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7833.042 | 0.9655 | 0.9331 | 1.0332 | |
| HCC1937 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7833.042 | 1.0405 | 1.0783 | 1.0332 | |
| HCC1937 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7833.042 | 0.7962 | 0.6041 | 1.0332 | |
| HCC1937 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7833.042 | 0.6768 | 0.3706 | 1.0332 | |
| HCC1937 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7833.042 | 0.6734 | 0.3640 | 1.0332 | |
| HCC1937 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7833.042 | 0.6205 | 0.2602 | 1.0332 | |
| HCC1937 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7833.042 | 0.5657 | 0.1522 | 1.0332 | |
| HCC1937 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7833.042 | 0.0360 | -0.9198 | 1.0332 | |
| HCC1937 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7834.018 | 0.9793 | 0.9781 | 1.8951 | |
| HCC1937 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7834.018 | 1.0647 | 1.0673 | 1.8951 |