Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.00427 | uM | 10578.141 | 0.9457 | 0.9300 | 1.5679 | |
| HCC38 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.0213 | uM | 10578.141 | 0.9506 | 0.9365 | 1.5679 | |
| HCC38 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.107 | uM | 10578.141 | 0.9600 | 0.9487 | 1.5679 | |
| HCC38 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.533 | uM | 10578.141 | 0.9018 | 0.8724 | 1.5679 | |
| HCC38 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 2.67 | uM | 10578.141 | 0.9646 | 0.9545 | 1.5679 | |
| HCC38 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 13.3 | uM | 10578.141 | 0.8084 | 0.7463 | 1.5679 | |
| HCC38 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 66.7 | uM | 10578.141 | 0.8149 | 0.7552 | 1.5679 | |
| HCC38 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.000171 | uM | 11850.158 | 0.9349 | 0.9333 | 1.9855 | |
| HCC38 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.000853 | uM | 11850.158 | 0.9221 | 0.9200 | 1.9855 | |
| HCC38 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.00427 | uM | 11850.158 | 1.0192 | 1.0193 | 1.9855 | |
| HCC38 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.0213 | uM | 11850.158 | 1.0547 | 1.0544 | 1.9855 | |
| HCC38 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.107 | uM | 11850.158 | 0.9683 | 0.9678 | 1.9855 | |
| HCC38 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.533 | uM | 11850.158 | 1.0126 | 1.0127 | 1.9855 | |
| HCC38 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 2.67 | uM | 11850.158 | 0.8099 | 0.7985 | 1.9855 | |
| HCC38 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 13.3 | uM | 11850.158 | 0.8446 | 0.8369 | 1.9855 | |
| HCC38 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 66.7 | uM | 11850.158 | 0.7836 | 0.7689 | 1.9855 | |
| HCC70 | TNBC | Basal A | AS-252424 | PI3K | PI3K | 0.0000853 | uM | 10873.153 | 0.9737 | 0.9606 | 1.3397 | |
| HCC70 | TNBC | Basal A | AS-252424 | PI3K | PI3K | 0.000427 | uM | 10873.153 | 0.9757 | 0.9636 | 1.3397 | |
| HCC70 | TNBC | Basal A | AS-252424 | PI3K | PI3K | 0.00213 | uM | 10873.153 | 0.9534 | 0.9301 | 1.3397 | |
| HCC70 | TNBC | Basal A | AS-252424 | PI3K | PI3K | 0.0107 | uM | 10873.153 | 1.0273 | 1.0406 | 1.3397 | |
| HCC70 | TNBC | Basal A | AS-252424 | PI3K | PI3K | 0.0533 | uM | 10873.153 | 0.9420 | 0.9127 | 1.3397 | |
| HCC70 | TNBC | Basal A | AS-252424 | PI3K | PI3K | 0.267 | uM | 10873.153 | 0.9437 | 0.9154 | 1.3397 | |
| HCC70 | TNBC | Basal A | AS-252424 | PI3K | PI3K | 1.33 | uM | 10873.153 | 0.8651 | 0.7949 | 1.3397 | |
| HCC70 | TNBC | Basal A | AS-252424 | PI3K | PI3K | 6.67 | uM | 10873.153 | 0.8865 | 0.8281 | 1.3397 | |
| HCC70 | TNBC | Basal A | AS-252424 | PI3K | PI3K | 33.3 | uM | 10873.153 | 0.6306 | 0.4177 | 1.3397 |