Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 15.2 | uM | 7474.065 | 0.7777 | 0.8377 | 2.9702 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 75.8 | uM | 7474.065 | 0.8269 | 0.8760 | 2.9702 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 379 | uM | 7474.065 | 0.7314 | 0.8001 | 2.9702 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 1890 | uM | 7474.065 | 0.6889 | 0.7642 | 2.9702 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.00485 | uM | 7475.065 | 1.2037 | 1.1463 | 2.6262 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.0243 | uM | 7475.065 | 1.1702 | 1.1233 | 2.6262 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.121 | uM | 7475.065 | 1.0754 | 1.0561 | 2.6262 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.606 | uM | 7475.065 | 1.2069 | 1.1485 | 2.6262 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 3.03 | uM | 7475.065 | 1.0990 | 1.0732 | 2.6262 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 15.2 | uM | 7475.065 | 1.0519 | 1.0389 | 2.6262 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 75.8 | uM | 7475.065 | 1.0284 | 1.0214 | 2.6262 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 379 | uM | 7475.065 | 1.0902 | 1.0669 | 2.6262 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 1890 | uM | 7475.065 | 1.0606 | 1.0453 | 2.6262 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.00485 | uM | 10379.065 | 1.0885 | 1.0770 | 2.2436 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.0243 | uM | 10379.065 | 0.9991 | 0.9992 | 2.2436 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.121 | uM | 10379.065 | 0.9680 | 0.9712 | 2.2436 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.606 | uM | 10379.065 | 1.0219 | 1.0194 | 2.2436 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 3.03 | uM | 10379.065 | 1.0532 | 1.0468 | 2.2436 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 15.2 | uM | 10379.065 | 1.0176 | 1.0156 | 2.2436 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 75.8 | uM | 10379.065 | 0.9979 | 0.9982 | 2.2436 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 379 | uM | 10379.065 | 0.8529 | 0.8630 | 2.2436 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 1890 | uM | 10379.065 | 0.7556 | 0.7651 | 2.2436 | |
| LY2 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.00485 | uM | 7477.065 | 1.4055 | 2.0786 | 0.7891 | |
| LY2 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.0243 | uM | 7477.065 | 1.7044 | 2.9309 | 0.7891 | |
| LY2 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.121 | uM | 7477.065 | 1.1958 | 1.5086 | 0.7891 |