Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7870.016 | 0.2743 | 0.0816 | 2.1045 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 9551.132 | 1.0457 | 1.0315 | 2.8612 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 9551.132 | 0.9854 | 0.9897 | 2.8612 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 9551.132 | 0.5647 | 0.6379 | 2.8612 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 9551.132 | 0.9717 | 0.9800 | 2.8612 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 9551.132 | 1.0388 | 1.0268 | 2.8612 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 9551.132 | 0.9740 | 0.9817 | 2.8612 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 9551.132 | 0.7197 | 0.7828 | 2.8612 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 9551.132 | 0.7433 | 0.8030 | 2.8612 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 9551.132 | 0.9969 | 0.9978 | 2.8612 | ||
| MCF 10F | NM | - | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7488.016 | 1.0830 | 1.1346 | 1.2238 | ||
| MCF 10F | NM | - | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7488.016 | 0.9252 | 0.8769 | 1.2238 | ||
| MCF 10F | NM | - | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7488.016 | 0.9620 | 0.9377 | 1.2238 | ||
| MCF 10F | NM | - | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7488.016 | 1.1236 | 1.1999 | 1.2238 | ||
| MCF 10F | NM | - | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7488.016 | 0.9722 | 0.9544 | 1.2238 | ||
| MCF 10F | NM | - | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7488.016 | 0.9735 | 0.9566 | 1.2238 | ||
| MCF 10F | NM | - | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7488.016 | 0.8791 | 0.8001 | 1.2238 | ||
| MCF 10F | NM | - | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7488.016 | 0.8390 | 0.7328 | 1.2238 | ||
| MCF 10F | NM | - | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7488.016 | 0.9378 | 0.8978 | 1.2238 | ||
| MCF 10F | NM | - | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7871.016 | 1.0926 | 1.1802 | 1.0272 | ||
| MCF 10F | NM | - | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7871.016 | 0.9782 | 0.9576 | 1.0272 | ||
| MCF 10F | NM | - | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7871.016 | 1.1009 | 1.1963 | 1.0272 | ||
| MCF 10F | NM | - | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7871.016 | 1.0326 | 1.0634 | 1.0272 | ||
| MCF 10F | NM | - | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7871.016 | 1.1050 | 1.2041 | 1.0272 | ||
| MCF 10F | NM | - | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7871.016 | 1.0738 | 1.1436 | 1.0272 |