Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-415 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.000171 | uM | 10938.147 | 1.0128 | 1.0282 | 0.9050 | |
| MDA-MB-415 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.000853 | uM | 10938.147 | 0.9316 | 0.8494 | 0.9050 | |
| MDA-MB-415 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.00427 | uM | 10938.147 | 0.9314 | 0.8490 | 0.9050 | |
| MDA-MB-415 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.0213 | uM | 10938.147 | 0.9250 | 0.8348 | 0.9050 | |
| MDA-MB-415 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.107 | uM | 10938.147 | 0.8956 | 0.7706 | 0.9050 | |
| MDA-MB-415 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.533 | uM | 10938.147 | 0.9195 | 0.8228 | 0.9050 | |
| MDA-MB-415 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 2.67 | uM | 10938.147 | 0.1939 | -0.6736 | 0.9050 | |
| MDA-MB-415 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 13.3 | uM | 10938.147 | 0.0455 | -0.9343 | 0.9050 | |
| MDA-MB-415 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 66.7 | uM | 10938.147 | 0.0081 | -0.9902 | 0.9050 | |
| MDA-MB-415 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.000171 | uM | 12333.147 | 0.8850 | 0.6723 | 0.6826 | |
| MDA-MB-415 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.000853 | uM | 12333.147 | 0.8858 | 0.6744 | 0.6826 | |
| MDA-MB-415 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.00427 | uM | 12333.147 | 0.9821 | 0.9477 | 0.6826 | |
| MDA-MB-415 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.0213 | uM | 12333.147 | 1.0443 | 1.1312 | 0.6826 | |
| MDA-MB-415 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.107 | uM | 12333.147 | 0.8759 | 0.6472 | 0.6826 | |
| MDA-MB-415 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.533 | uM | 12333.147 | 0.7301 | 0.2614 | 0.6826 | |
| MDA-MB-415 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 2.67 | uM | 12333.147 | 0.3693 | -0.5353 | 0.6826 | |
| MDA-MB-415 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 13.3 | uM | 12333.147 | 0.0312 | -0.9875 | 0.6826 | |
| MDA-MB-415 | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 66.7 | uM | 12333.147 | 0.0192 | -0.9939 | 0.6826 | |
| MDA-MB-453 | TNBC | Luminal | Oxamflatin | HDAC | HDAC | 0.000171 | uM | 12414.147 | 0.9631 | 0.9345 | 1.1273 | |
| MDA-MB-453 | TNBC | Luminal | Oxamflatin | HDAC | HDAC | 0.000853 | uM | 12414.147 | 0.9217 | 0.8604 | 1.1273 | |
| MDA-MB-453 | TNBC | Luminal | Oxamflatin | HDAC | HDAC | 0.00427 | uM | 12414.147 | 0.9538 | 0.9178 | 1.1273 | |
| MDA-MB-453 | TNBC | Luminal | Oxamflatin | HDAC | HDAC | 0.0213 | uM | 12414.147 | 0.9096 | 0.8387 | 1.1273 | |
| MDA-MB-453 | TNBC | Luminal | Oxamflatin | HDAC | HDAC | 0.107 | uM | 12414.147 | 0.8356 | 0.7054 | 1.1273 | |
| MDA-MB-453 | TNBC | Luminal | Oxamflatin | HDAC | HDAC | 0.533 | uM | 12414.147 | 0.5873 | 0.2474 | 1.1273 | |
| MDA-MB-453 | TNBC | Luminal | Oxamflatin | HDAC | HDAC | 2.67 | uM | 12414.147 | 0.0669 | -0.8184 | 1.1273 |