Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1954 | HER2amp | Basal A | Oxamflatin | HDAC | HDAC | 0.000171 | uM | 11055.147 | 0.9978 | 0.9974 | 1.6841 | |
| HCC1954 | HER2amp | Basal A | Oxamflatin | HDAC | HDAC | 0.000853 | uM | 11055.147 | 0.9476 | 0.9371 | 1.6841 | |
| HCC1954 | HER2amp | Basal A | Oxamflatin | HDAC | HDAC | 0.00427 | uM | 11055.147 | 0.9637 | 0.9565 | 1.6841 | |
| HCC1954 | HER2amp | Basal A | Oxamflatin | HDAC | HDAC | 0.0213 | uM | 11055.147 | 0.9076 | 0.8882 | 1.6841 | |
| HCC1954 | HER2amp | Basal A | Oxamflatin | HDAC | HDAC | 0.107 | uM | 11055.147 | 0.9169 | 0.8996 | 1.6841 | |
| HCC1954 | HER2amp | Basal A | Oxamflatin | HDAC | HDAC | 0.533 | uM | 11055.147 | 0.8220 | 0.7802 | 1.6841 | |
| HCC1954 | HER2amp | Basal A | Oxamflatin | HDAC | HDAC | 2.67 | uM | 11055.147 | 0.5420 | 0.3903 | 1.6841 | |
| HCC1954 | HER2amp | Basal A | Oxamflatin | HDAC | HDAC | 13.3 | uM | 11055.147 | 0.2054 | -0.2186 | 1.6841 | |
| HCC1954 | HER2amp | Basal A | Oxamflatin | HDAC | HDAC | 66.7 | uM | 11055.147 | 0.0117 | -0.8576 | 1.6841 | |
| HCC2185 | TNBC | Luminal | Oxamflatin | HDAC | HDAC | 0.000171 | uM | 10996.147 | 0.9987 | 0.9957 | 0.6261 | |
| HCC2185 | TNBC | Luminal | Oxamflatin | HDAC | HDAC | 0.000853 | uM | 10996.147 | 0.9685 | 0.9002 | 0.6261 | |
| HCC2185 | TNBC | Luminal | Oxamflatin | HDAC | HDAC | 0.00427 | uM | 10996.147 | 0.9388 | 0.8081 | 0.6261 | |
| HCC2185 | TNBC | Luminal | Oxamflatin | HDAC | HDAC | 0.0213 | uM | 10996.147 | 0.9860 | 0.9554 | 0.6261 | |
| HCC2185 | TNBC | Luminal | Oxamflatin | HDAC | HDAC | 0.107 | uM | 10996.147 | 0.9379 | 0.8053 | 0.6261 | |
| HCC2185 | TNBC | Luminal | Oxamflatin | HDAC | HDAC | 0.533 | uM | 10996.147 | 0.7923 | 0.3788 | 0.6261 | |
| HCC2185 | TNBC | Luminal | Oxamflatin | HDAC | HDAC | 2.67 | uM | 10996.147 | 0.3082 | -0.6949 | 0.6261 | |
| HCC2185 | TNBC | Luminal | Oxamflatin | HDAC | HDAC | 13.3 | uM | 10996.147 | 0.0253 | -0.9944 | 0.6261 | |
| HCC2185 | TNBC | Luminal | Oxamflatin | HDAC | HDAC | 66.7 | uM | 10996.147 | 0.0140 | -0.9978 | 0.6261 | |
| HCC2185 | TNBC | Luminal | Oxamflatin | HDAC | HDAC | 0.000171 | uM | 12192.147 | 0.9873 | 0.9551 | 0.5645 | |
| HCC2185 | TNBC | Luminal | Oxamflatin | HDAC | HDAC | 0.000853 | uM | 12192.147 | 1.0298 | 1.1069 | 0.5645 | |
| HCC2185 | TNBC | Luminal | Oxamflatin | HDAC | HDAC | 0.00427 | uM | 12192.147 | 0.9319 | 0.7650 | 0.5645 | |
| HCC2185 | TNBC | Luminal | Oxamflatin | HDAC | HDAC | 0.0213 | uM | 12192.147 | 1.0309 | 1.1107 | 0.5645 | |
| HCC2185 | TNBC | Luminal | Oxamflatin | HDAC | HDAC | 0.107 | uM | 12192.147 | 0.8472 | 0.4910 | 0.5645 | |
| HCC2185 | TNBC | Luminal | Oxamflatin | HDAC | HDAC | 0.533 | uM | 12192.147 | 0.7655 | 0.2457 | 0.5645 | |
| HCC2185 | TNBC | Luminal | Oxamflatin | HDAC | HDAC | 2.67 | uM | 12192.147 | 0.2964 | -0.7679 | 0.5645 |