Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 12428.147 | 1.0411 | 1.1198 | 0.6926 | |
| SUM1315MO2 | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.213 | uM | 12428.147 | 1.0404 | 1.1177 | 0.6926 | |
| SUM1315MO2 | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 1.07 | uM | 12428.147 | 0.9632 | 0.8946 | 0.6926 | |
| SUM1315MO2 | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 5.33 | uM | 12428.147 | 0.6791 | 0.1437 | 0.6926 | |
| SUM1315MO2 | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 26.7 | uM | 12428.147 | 0.0685 | -0.9583 | 0.6926 | |
| SUM1315MO2 | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 133 | uM | 12428.147 | 0.0583 | -0.9670 | 0.6926 | |
| SUM149PT | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 10819.147 | 1.0227 | 1.0209 | 2.1652 | |
| SUM149PT | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 10819.147 | 0.9729 | 0.9748 | 2.1652 | |
| SUM149PT | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 10819.147 | 0.9455 | 0.9489 | 2.1652 | |
| SUM149PT | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 10819.147 | 0.9563 | 0.9591 | 2.1652 | |
| SUM149PT | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.213 | uM | 10819.147 | 1.0242 | 1.0222 | 2.1652 | |
| SUM149PT | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 1.07 | uM | 10819.147 | 0.9683 | 0.9705 | 2.1652 | |
| SUM149PT | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 5.33 | uM | 10819.147 | 0.8025 | 0.8068 | 2.1652 | |
| SUM149PT | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 26.7 | uM | 10819.147 | 0.0117 | -0.7433 | 2.1652 | |
| SUM149PT | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 133 | uM | 10819.147 | 0.0101 | -0.7606 | 2.1652 | |
| SUM149PT | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 11937.147 | 1.0026 | 1.0022 | 2.3986 | |
| SUM149PT | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 11937.147 | 0.9986 | 0.9988 | 2.3986 | |
| SUM149PT | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 11937.147 | 1.0188 | 1.0156 | 2.3986 | |
| SUM149PT | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 11937.147 | 1.0575 | 1.0472 | 2.3986 | |
| SUM149PT | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.213 | uM | 11937.147 | 1.0031 | 1.0026 | 2.3986 | |
| SUM149PT | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 1.07 | uM | 11937.147 | 0.9300 | 0.9404 | 2.3986 | |
| SUM149PT | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 5.33 | uM | 11937.147 | 0.6022 | 0.6189 | 2.3986 | |
| SUM149PT | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 26.7 | uM | 11937.147 | 0.0167 | -0.6373 | 2.3986 | |
| SUM149PT | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 133 | uM | 11937.147 | 0.0077 | -0.7378 | 2.3986 | |
| SUM159PT | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 11057.147 | 0.9491 | 0.9739 | 3.9818 |