Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7473.066 | 1.2172 | 1.1738 | 2.3582 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7473.066 | 1.7733 | 1.5499 | 2.3582 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7473.066 | 0.8527 | 0.8693 | 2.3582 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7474.066 | 0.9399 | 0.9561 | 2.7948 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7474.066 | 0.9826 | 0.9874 | 2.7948 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7474.066 | 0.9567 | 0.9686 | 2.7948 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7474.066 | 0.9718 | 0.9797 | 2.7948 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7474.066 | 1.0933 | 1.0649 | 2.7948 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7474.066 | 1.0521 | 1.0367 | 2.7948 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7474.066 | 1.0799 | 1.0558 | 2.7948 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7474.066 | 0.9933 | 0.9952 | 2.7948 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7474.066 | 0.6780 | 0.7403 | 2.7948 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7475.066 | 1.0286 | 1.0205 | 2.7689 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7475.066 | 1.1895 | 1.1293 | 2.7689 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7475.066 | 1.0394 | 1.0281 | 2.7689 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7475.066 | 0.9755 | 0.9821 | 2.7689 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7475.066 | 1.2642 | 1.1767 | 2.7689 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7475.066 | 1.1670 | 1.1147 | 2.7689 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7475.066 | 1.2864 | 1.1905 | 2.7689 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7475.066 | 1.0245 | 1.0176 | 2.7689 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7475.066 | 0.9673 | 0.9761 | 2.7689 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 10379.066 | 1.0385 | 1.0319 | 2.3931 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 10379.066 | 1.0179 | 1.0149 | 2.3931 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 10379.066 | 0.9840 | 0.9865 | 2.3931 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 10379.066 | 1.0514 | 1.0423 | 2.3931 |