Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-175-VII | HR+ | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 7500.066 | 0.9682 | 0.9188 | 0.7802 | |
| MDA-MB-175-VII | HR+ | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 7500.066 | 0.7973 | 0.4961 | 0.7802 | |
| MDA-MB-175-VII | HR+ | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 7500.066 | 0.9058 | 0.7619 | 0.7802 | |
| MDA-MB-231 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7504.066 | 1.0124 | 1.0134 | 1.8487 | |
| MDA-MB-231 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.000427 | uM | 7504.066 | 1.2473 | 1.2540 | 1.8487 | |
| MDA-MB-231 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.00213 | uM | 7504.066 | 1.1917 | 1.1991 | 1.8487 | |
| MDA-MB-231 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0107 | uM | 7504.066 | 1.3321 | 1.3356 | 1.8487 | |
| MDA-MB-231 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0533 | uM | 7504.066 | 1.0859 | 1.0912 | 1.8487 | |
| MDA-MB-231 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.267 | uM | 7504.066 | 1.2037 | 1.2109 | 1.8487 | |
| MDA-MB-231 | TNBC | Basal B | AG1024 | IGF1R | RTK | 1.33 | uM | 7504.066 | 1.0245 | 1.0263 | 1.8487 | |
| MDA-MB-231 | TNBC | Basal B | AG1024 | IGF1R | RTK | 6.67 | uM | 7504.066 | 1.1702 | 1.1775 | 1.8487 | |
| MDA-MB-231 | TNBC | Basal B | AG1024 | IGF1R | RTK | 33.3 | uM | 7504.066 | 0.6896 | 0.6357 | 1.8487 | |
| MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7506.066 | 0.9856 | 0.9749 | 1.1486 | |
| MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 7506.066 | 0.9448 | 0.9035 | 1.1486 | |
| MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 7506.066 | 0.9485 | 0.9099 | 1.1486 | |
| MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 7506.066 | 1.0085 | 1.0147 | 1.1486 | |
| MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0533 | uM | 7506.066 | 0.9672 | 0.9427 | 1.1486 | |
| MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.267 | uM | 7506.066 | 0.9409 | 0.8967 | 1.1486 | |
| MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 1.33 | uM | 7506.066 | 0.9155 | 0.8521 | 1.1486 | |
| MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 6.67 | uM | 7506.066 | 0.9846 | 0.9732 | 1.1486 | |
| MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 33.3 | uM | 7506.066 | 0.9638 | 0.9368 | 1.1486 | |
| MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7507.066 | 0.9621 | 0.9171 | 0.9124 | |
| MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.000427 | uM | 7507.066 | 0.9812 | 0.9588 | 0.9124 | |
| MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.00213 | uM | 7507.066 | 0.9919 | 0.9821 | 0.9124 | |
| MDA-MB-361 | HER2amp | Luminal | AG1024 | IGF1R | RTK | 0.0107 | uM | 7507.066 | 0.9700 | 0.9343 | 0.9124 |