Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 11852.145 | 0.0535 | -0.6956 | 1.5550 | |
SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 11852.145 | 0.0535 | -0.6956 | 1.5550 | |
SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 11852.145 | 0.0491 | -0.7121 | 1.5550 | |
SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 11852.145 | 0.0491 | -0.7121 | 1.5550 | |
SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 11852.145 | 0.0483 | -0.7150 | 1.5550 | |
SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 11852.145 | 0.0483 | -0.7150 | 1.5550 | |
SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14290.189 | 1.0072 | 1.0275 | 0.5261 | |
SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14290.189 | 1.0072 | 1.0275 | 0.5261 | |
SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14290.189 | 0.9956 | 0.9833 | 0.5261 | |
SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14290.189 | 0.9956 | 0.9833 | 0.5261 | |
SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14290.189 | 1.0055 | 1.0209 | 0.5261 | |
SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14290.189 | 1.0055 | 1.0209 | 0.5261 | |
SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14290.189 | 0.9609 | 0.8540 | 0.5261 | |
SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14290.189 | 0.9609 | 0.8540 | 0.5261 | |
SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14290.189 | 0.8518 | 0.4745 | 0.5261 | |
SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14290.189 | 0.8518 | 0.4745 | 0.5261 | |
SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14290.189 | 0.4454 | -0.5702 | 0.5261 | |
SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14290.189 | 0.4454 | -0.5702 | 0.5261 | |
SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14290.189 | 0.3743 | -0.6912 | 0.5261 | |
SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14290.189 | 0.3743 | -0.6912 | 0.5261 | |
SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14290.189 | 0.3004 | -0.7967 | 0.5261 | |
SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14290.189 | 0.3004 | -0.7967 | 0.5261 | |
SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14290.189 | 0.7429 | 0.1367 | 0.5261 | |
SUM52PE | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14290.189 | 0.7429 | 0.1367 | 0.5261 | |
T47D | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10939.145 | 0.9805 | 0.9764 | 1.6558 |