Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-361	HER2amp	Luminal	MG-132	Proteasome	Proteasome	0.000853	uM	12379.17	0.9883	0.9598	0.5805
MDA-MB-361	HER2amp	Luminal	MG-132	Proteasome	Proteasome	0.000853	uM	12379.17	0.9883	0.9598	0.5805
MDA-MB-361	HER2amp	Luminal	MG-132	Proteasome	Proteasome	0.00427	uM	12379.17	1.0026	1.0089	0.5805
MDA-MB-361	HER2amp	Luminal	MG-132	Proteasome	Proteasome	0.00427	uM	12379.17	1.0026	1.0089	0.5805
MDA-MB-361	HER2amp	Luminal	MG-132	Proteasome	Proteasome	0.0213	uM	12379.17	0.9973	0.9905	0.5805
MDA-MB-361	HER2amp	Luminal	MG-132	Proteasome	Proteasome	0.0213	uM	12379.17	0.9973	0.9905	0.5805
MDA-MB-361	HER2amp	Luminal	MG-132	Proteasome	Proteasome	0.107	uM	12379.17	0.9781	0.9250	0.5805
MDA-MB-361	HER2amp	Luminal	MG-132	Proteasome	Proteasome	0.107	uM	12379.17	0.9781	0.9250	0.5805
MDA-MB-361	HER2amp	Luminal	MG-132	Proteasome	Proteasome	0.533	uM	12379.17	0.2904	-0.7623	0.5805
MDA-MB-361	HER2amp	Luminal	MG-132	Proteasome	Proteasome	0.533	uM	12379.17	0.2904	-0.7623	0.5805
MDA-MB-361	HER2amp	Luminal	MG-132	Proteasome	Proteasome	2.67	uM	12379.17	0.1063	-0.9579	0.5805
MDA-MB-361	HER2amp	Luminal	MG-132	Proteasome	Proteasome	2.67	uM	12379.17	0.1063	-0.9579	0.5805
MDA-MB-361	HER2amp	Luminal	MG-132	Proteasome	Proteasome	13.3	uM	12379.17	0.0230	-0.9970	0.5805
MDA-MB-361	HER2amp	Luminal	MG-132	Proteasome	Proteasome	13.3	uM	12379.17	0.0230	-0.9970	0.5805
MDA-MB-361	HER2amp	Luminal	MG-132	Proteasome	Proteasome	66.7	uM	12379.17	0.0224	-0.9971	0.5805
MDA-MB-361	HER2amp	Luminal	MG-132	Proteasome	Proteasome	66.7	uM	12379.17	0.0224	-0.9971	0.5805
MDA-MB-415	HR+	Luminal	MG-132	Proteasome	Proteasome	0.000171	uM	10938.145	0.9126	0.8414	1.1073
MDA-MB-415	HR+	Luminal	MG-132	Proteasome	Proteasome	0.000171	uM	10938.145	0.9126	0.8414	1.1073
MDA-MB-415	HR+	Luminal	MG-132	Proteasome	Proteasome	0.000853	uM	10938.145	0.8212	0.6741	1.1073
MDA-MB-415	HR+	Luminal	MG-132	Proteasome	Proteasome	0.000853	uM	10938.145	0.8212	0.6741	1.1073
MDA-MB-415	HR+	Luminal	MG-132	Proteasome	Proteasome	0.00427	uM	10938.145	0.8438	0.7157	1.1073
MDA-MB-415	HR+	Luminal	MG-132	Proteasome	Proteasome	0.00427	uM	10938.145	0.8438	0.7157	1.1073
MDA-MB-415	HR+	Luminal	MG-132	Proteasome	Proteasome	0.0213	uM	10938.145	0.7964	0.6283	1.1073
MDA-MB-415	HR+	Luminal	MG-132	Proteasome	Proteasome	0.0213	uM	10938.145	0.7964	0.6283	1.1073
MDA-MB-415	HR+	Luminal	MG-132	Proteasome	Proteasome	0.107	uM	10938.145	0.6049	0.2703	1.1073

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)