Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14619.189 | 0.9676 | 0.9492 | 1.2787 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14619.189 | 0.9676 | 0.9492 | 1.2787 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14619.189 | 0.9626 | 0.9412 | 1.2787 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14619.189 | 0.9626 | 0.9412 | 1.2787 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14619.189 | 0.4265 | 0.0270 | 1.2787 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14619.189 | 0.4265 | 0.0270 | 1.2787 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14619.189 | 0.0273 | -0.8802 | 1.2787 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14619.189 | 0.0273 | -0.8802 | 1.2787 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14619.189 | 0.0393 | -0.8410 | 1.2787 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14619.189 | 0.0393 | -0.8410 | 1.2787 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14619.189 | 0.0461 | -0.8197 | 1.2787 | |
| MDA-MB-175-VII | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14619.189 | 0.0461 | -0.8197 | 1.2787 | |
| MDA-MB-361 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10643.145 | 1.0549 | 1.2609 | 0.4356 | |
| MDA-MB-361 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10643.145 | 1.0549 | 1.2609 | 0.4356 | |
| MDA-MB-361 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10643.145 | 1.0611 | 1.2916 | 0.4356 | |
| MDA-MB-361 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10643.145 | 1.0611 | 1.2916 | 0.4356 | |
| MDA-MB-361 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10643.145 | 0.9881 | 0.9459 | 0.4356 | |
| MDA-MB-361 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10643.145 | 0.9881 | 0.9459 | 0.4356 | |
| MDA-MB-361 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10643.145 | 1.0480 | 1.2274 | 0.4356 | |
| MDA-MB-361 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10643.145 | 1.0480 | 1.2274 | 0.4356 | |
| MDA-MB-361 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10643.145 | 0.9552 | 0.8002 | 0.4356 | |
| MDA-MB-361 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10643.145 | 0.9552 | 0.8002 | 0.4356 | |
| MDA-MB-361 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10643.145 | 0.5572 | -0.4778 | 0.4356 | |
| MDA-MB-361 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10643.145 | 0.5572 | -0.4778 | 0.4356 | |
| MDA-MB-361 | HER2amp | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10643.145 | 0.3549 | -0.8146 | 0.4356 |