Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47DKBLUC | Unknown | Unknown | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 33.3 | uM | 12608.167 | 0.1320 | -0.5949 | 1.2681 | |
| UACC-812 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.000256 | uM | 10580.142 | 1.0597 | 1.1495 | 0.8039 | |
| UACC-812 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.00128 | uM | 10580.142 | 0.9264 | 0.8187 | 0.8039 | |
| UACC-812 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0064 | uM | 10580.142 | 0.9999 | 0.9998 | 0.8039 | |
| UACC-812 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.032 | uM | 10580.142 | 0.9652 | 0.9138 | 0.8039 | |
| UACC-812 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.16 | uM | 10580.142 | 1.0012 | 1.0031 | 0.8039 | |
| UACC-812 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.8 | uM | 10580.142 | 0.9094 | 0.7771 | 0.8039 | |
| UACC-812 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 4 | uM | 10580.142 | 0.6080 | 0.0771 | 0.8039 | |
| UACC-812 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 20 | uM | 10580.142 | 0.0606 | -0.9389 | 0.8039 | |
| UACC-812 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 100 | uM | 10580.142 | 0.0293 | -0.9752 | 0.8039 | |
| UACC-812 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0000853 | uM | 10754.154 | 1.0074 | 1.0107 | 1.3934 | |
| UACC-812 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.000427 | uM | 10754.154 | 0.9409 | 0.9144 | 1.3934 | |
| UACC-812 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.00213 | uM | 10754.154 | 1.0665 | 1.0946 | 1.3934 | |
| UACC-812 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0107 | uM | 10754.154 | 1.1265 | 1.1784 | 1.3934 | |
| UACC-812 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0533 | uM | 10754.154 | 0.9880 | 0.9828 | 1.3934 | |
| UACC-812 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.267 | uM | 10754.154 | 0.8541 | 0.7860 | 1.3934 | |
| UACC-812 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 1.33 | uM | 10754.154 | 0.7413 | 0.6133 | 1.3934 | |
| UACC-812 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 6.67 | uM | 10754.154 | 0.4123 | 0.0589 | 1.3934 | |
| UACC-812 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 33.3 | uM | 10754.154 | 0.0012 | -0.9836 | 1.3934 | |
| UACC-812 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0000853 | uM | 11938.154 | 0.9427 | 0.8232 | 0.6375 | |
| UACC-812 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.000427 | uM | 11938.154 | 0.8725 | 0.6148 | 0.6375 | |
| UACC-812 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.00213 | uM | 11938.154 | 0.9633 | 0.8859 | 0.6375 | |
| UACC-812 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0107 | uM | 11938.154 | 0.9141 | 0.7371 | 0.6375 | |
| UACC-812 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.0533 | uM | 11938.154 | 0.9211 | 0.7582 | 0.6375 | |
| UACC-812 | HER2amp | Luminal | Lestaurtinib | FLT3/JAK2/TrkA | RTK | 0.267 | uM | 11938.154 | 0.8736 | 0.6180 | 0.6375 |