Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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184A1 | NM | Basal | AG1024 | IGF1R | RTK | 0.000427 | uM | 5895.066 | 1.0313 | 1.0537 | 1.1612 | |
184A1 | NM | Basal | AG1024 | IGF1R | RTK | 0.00213 | uM | 5895.066 | 0.9889 | 0.9809 | 1.1612 | |
184A1 | NM | Basal | AG1024 | IGF1R | RTK | 0.0107 | uM | 5895.066 | 1.0087 | 1.0150 | 1.1612 | |
184A1 | NM | Basal | AG1024 | IGF1R | RTK | 0.0533 | uM | 5895.066 | 0.9029 | 0.8316 | 1.1612 | |
184A1 | NM | Basal | AG1024 | IGF1R | RTK | 0.267 | uM | 5895.066 | 0.6414 | 0.3643 | 1.1612 | |
184A1 | NM | Basal | AG1024 | IGF1R | RTK | 1.33 | uM | 5895.066 | 0.4503 | 0.0061 | 1.1612 | |
184A1 | NM | Basal | AG1024 | IGF1R | RTK | 6.67 | uM | 5895.066 | 0.3682 | -0.1540 | 1.1612 | |
184A1 | NM | Basal | AG1024 | IGF1R | RTK | 33.3 | uM | 5895.066 | 0.3447 | -0.2007 | 1.1612 | |
184B5 | NM | Basal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 5896.066 | 0.9676 | 0.9543 | 1.4224 | |
184B5 | NM | Basal | AG1024 | IGF1R | RTK | 0.000427 | uM | 5896.066 | 0.9588 | 0.9417 | 1.4224 | |
184B5 | NM | Basal | AG1024 | IGF1R | RTK | 0.00213 | uM | 5896.066 | 0.9808 | 0.9729 | 1.4224 | |
184B5 | NM | Basal | AG1024 | IGF1R | RTK | 0.0107 | uM | 5896.066 | 1.0272 | 1.0382 | 1.4224 | |
184B5 | NM | Basal | AG1024 | IGF1R | RTK | 0.0533 | uM | 5896.066 | 1.0135 | 1.0189 | 1.4224 | |
184B5 | NM | Basal | AG1024 | IGF1R | RTK | 0.267 | uM | 5896.066 | 0.5022 | 0.2324 | 1.4224 | |
184B5 | NM | Basal | AG1024 | IGF1R | RTK | 1.33 | uM | 5896.066 | 0.4708 | 0.1777 | 1.4224 | |
184B5 | NM | Basal | AG1024 | IGF1R | RTK | 6.67 | uM | 5896.066 | 0.3698 | -0.0062 | 1.4224 | |
184B5 | NM | Basal | AG1024 | IGF1R | RTK | 33.3 | uM | 5896.066 | 0.2954 | -0.1513 | 1.4224 | |
184B5 | NM | Basal | AG1024 | IGF1R | RTK | 0.0000853 | uM | 5897.066 | 1.0366 | 1.0572 | 1.2737 | |
184B5 | NM | Basal | AG1024 | IGF1R | RTK | 0.000427 | uM | 5897.066 | 1.0104 | 1.0163 | 1.2737 | |
184B5 | NM | Basal | AG1024 | IGF1R | RTK | 0.00213 | uM | 5897.066 | 1.0310 | 1.0485 | 1.2737 | |
184B5 | NM | Basal | AG1024 | IGF1R | RTK | 0.0107 | uM | 5897.066 | 1.0145 | 1.0227 | 1.2737 | |
184B5 | NM | Basal | AG1024 | IGF1R | RTK | 0.0533 | uM | 5897.066 | 1.0277 | 1.0433 | 1.2737 | |
184B5 | NM | Basal | AG1024 | IGF1R | RTK | 0.267 | uM | 5897.066 | 0.5663 | 0.2798 | 1.2737 | |
184B5 | NM | Basal | AG1024 | IGF1R | RTK | 1.33 | uM | 5897.066 | 0.5288 | 0.2128 | 1.2737 | |
184B5 | NM | Basal | AG1024 | IGF1R | RTK | 6.67 | uM | 5897.066 | 0.3758 | -0.0724 | 1.2737 |