Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-157	TNBC	Basal B	LBH589	HDAC	HDAC	33.3	uM	12594.167	0.0091	-0.9284	1.4099
MDA-MB-175-VII	HR+	Luminal	LBH589	HDAC	HDAC	0.0000853	uM	10818.154	1.0034	1.0134	0.5056
MDA-MB-175-VII	HR+	Luminal	LBH589	HDAC	HDAC	0.000427	uM	10818.154	0.9314	0.7378	0.5056
MDA-MB-175-VII	HR+	Luminal	LBH589	HDAC	HDAC	0.00213	uM	10818.154	1.0018	1.0070	0.5056
MDA-MB-175-VII	HR+	Luminal	LBH589	HDAC	HDAC	0.0107	uM	10818.154	0.9674	0.8732	0.5056
MDA-MB-175-VII	HR+	Luminal	LBH589	HDAC	HDAC	0.0533	uM	10818.154	0.9801	0.9222	0.5056
MDA-MB-175-VII	HR+	Luminal	LBH589	HDAC	HDAC	0.267	uM	10818.154	0.9252	0.7147	0.5056
MDA-MB-175-VII	HR+	Luminal	LBH589	HDAC	HDAC	1.33	uM	10818.154	0.4732	-0.5447	0.5056
MDA-MB-175-VII	HR+	Luminal	LBH589	HDAC	HDAC	6.67	uM	10818.154	0.2420	-0.8791	0.5056
MDA-MB-175-VII	HR+	Luminal	LBH589	HDAC	HDAC	33.3	uM	10818.154	0.1844	-0.9294	0.5056
MDA-MB-175-VII	HR+	Luminal	LBH589	HDAC	HDAC	0.0000853	uM	12126.154	0.9479	0.8297	0.6012
MDA-MB-175-VII	HR+	Luminal	LBH589	HDAC	HDAC	0.000427	uM	12126.154	0.8853	0.6331	0.6012
MDA-MB-175-VII	HR+	Luminal	LBH589	HDAC	HDAC	0.00213	uM	12126.154	0.9573	0.8599	0.6012
MDA-MB-175-VII	HR+	Luminal	LBH589	HDAC	HDAC	0.0107	uM	12126.154	0.9613	0.8729	0.6012
MDA-MB-175-VII	HR+	Luminal	LBH589	HDAC	HDAC	0.0533	uM	12126.154	0.8901	0.6479	0.6012
MDA-MB-175-VII	HR+	Luminal	LBH589	HDAC	HDAC	0.267	uM	12126.154	0.8669	0.5770	0.6012
MDA-MB-175-VII	HR+	Luminal	LBH589	HDAC	HDAC	1.33	uM	12126.154	0.2991	-0.7314	0.6012
MDA-MB-175-VII	HR+	Luminal	LBH589	HDAC	HDAC	6.67	uM	12126.154	0.0671	-0.9776	0.6012
MDA-MB-175-VII	HR+	Luminal	LBH589	HDAC	HDAC	33.3	uM	12126.154	0.0556	-0.9836	0.6012
MDA-MB-361	HER2amp	Luminal	LBH589	HDAC	HDAC	0.0000853	uM	10999.154	1.0095	1.0272	0.7027
MDA-MB-361	HER2amp	Luminal	LBH589	HDAC	HDAC	0.000427	uM	10999.154	1.0105	1.0301	0.7027
MDA-MB-361	HER2amp	Luminal	LBH589	HDAC	HDAC	0.00213	uM	10999.154	1.0158	1.0450	0.7027
MDA-MB-361	HER2amp	Luminal	LBH589	HDAC	HDAC	0.0107	uM	10999.154	1.0721	1.2083	0.7027
MDA-MB-361	HER2amp	Luminal	LBH589	HDAC	HDAC	0.0533	uM	10999.154	0.7338	0.2875	0.7027
MDA-MB-361	HER2amp	Luminal	LBH589	HDAC	HDAC	0.267	uM	10999.154	0.0326	-0.9847	0.7027

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)